Gene: CCL2 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6347
Gene Symbol: CCL2
CCL2 		0.270 AlteredExpression disease BEFREE Activated IPF fibroblasts displayed the highest levels of contractility and CCL2 production. 30091381 2018
Entrez Id: 6347
Gene Symbol: CCL2
CCL2 		0.270 Therapeutic disease CTD_mouse Combinatorial treatment of idiopathic pulmonary fibrosis using nanoparticles with prostaglandin E and siRNA(s). 28434932 2017
Entrez Id: 6347
Gene Symbol: CCL2
CCL2 		0.270 Biomarker disease BEFREE Emerging pieces of evidence indicate that the CCL2/CCR2 axis is involved in fibrotic diseases, such as increased plasma levels of CCL2 and the presence of CCL2-hyperresponsive fibroblasts explanted from patients with systemic sclerosis and idiopathic pulmonary fibrosis. 24583146 2014
Entrez Id: 6347
Gene Symbol: CCL2
CCL2 		0.270 AlteredExpression disease BEFREE Primary human lung fibroblasts isolated from patients with idiopathic pulmonary fibrosis (IPF) produced significantly higher levels of CCL2 than nonfibrotic lung fibroblasts. 23583295 2013
Entrez Id: 6347
Gene Symbol: CCL2
CCL2 		0.270 AlteredExpression disease BEFREE In 16 sarcoidosis, 7 idiopathic pulmonary fibrosis (IPF) and 8 hypersensitivity pneumonitis (HP) patients we evaluated IL-1 alpha, -1R, -1RA, -2, -4, -4R alpha, -6, -10, -12, IFN-gamma, TGF-beta1 and TNF-alpha gene polymorphisms in peripheral blood, and MCP-1,MIP-1 alpha, MIP-1 beta, RANTES, ENA-78, FGF, G-CSF, GM-CSF, IFN-gamma, IL-1 alpha, IL-1RA, IL-1 beta, -2, -4, -5, -6, -8, -10, -17, TNF-alpha, Tpo and VEGF values in BALF. 19117745 2009
Entrez Id: 6347
Gene Symbol: CCL2
CCL2 		0.270 AlteredExpression disease BEFREE We report for the first time that PAR(1) and CCL2 are coexpressed and co-up-regulated on the activated epithelium in fibrotic areas in IPF. 19060230 2009
Entrez Id: 6347
Gene Symbol: CCL2
CCL2 		0.270 AlteredExpression disease LHGDN Hyper-responsiveness of IPF/UIP fibroblasts: interplay between TGFbeta1, IL-13 and CCL2. 18395486 2008
Entrez Id: 6347
Gene Symbol: CCL2
CCL2 		0.270 AlteredExpression disease BEFREE Macrophages and vascular endothelial and smooth muscle cells were shown to express MCP-1 in both IPF and non-IPF lung specimens. 1608944 1992