Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6392
Gene Symbol: SDHD
SDHD 		0.760 Biomarker disease GENOMICS_ENGLAND
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		0.760 Biomarker disease CTD_human
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		0.760 CausalMutation disease CLINVAR
Entrez Id: 6392
Gene Symbol: SDHD
SDHD 		0.760 Biomarker disease CTD_human
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		0.760 Biomarker disease GENOMICS_ENGLAND
Entrez Id: 6391
Gene Symbol: SDHC
SDHC 		0.620 Biomarker disease CTD_human
Entrez Id: 6391
Gene Symbol: SDHC
SDHC 		0.620 CausalMutation disease CLINVAR
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.300 Biomarker disease GENOMICS_ENGLAND
Entrez Id: 7428
Gene Symbol: VHL
VHL 		0.300 Biomarker disease GENOMICS_ENGLAND
Entrez Id: 55654
Gene Symbol: TMEM127
TMEM127 		0.300 Biomarker disease GENOMICS_ENGLAND
Entrez Id: 6392
Gene Symbol: SDHD
SDHD 		0.760 GeneticVariation disease CLINVAR Mutations in SDHD, a mitochondrial complex II gene, in hereditary paraganglioma. 10657297 2000
Entrez Id: 6392
Gene Symbol: SDHD
SDHD 		0.760 CausalMutation disease CLINVAR Mutations in SDHD, a mitochondrial complex II gene, in hereditary paraganglioma. 10657297 2000
Entrez Id: 6392
Gene Symbol: SDHD
SDHD 		0.760 CausalMutation disease CLINVAR Somatic and occult germ-line mutations in SDHD, a mitochondrial complex II gene, in nonfamilial pheochromocytoma. 11156372 2000
Entrez Id: 6392
Gene Symbol: SDHD
SDHD 		0.760 CausalMutation disease CLINVAR Germline SDHD mutation in familial phaeochromocytoma. 11323050 2001
Entrez Id: 6392
Gene Symbol: SDHD
SDHD 		0.760 CausalMutation disease CLINVAR Novel mutations in the SDHD gene in pedigrees with familial carotid body paraganglioma and sensorineural hearing loss. 11391796 2001
Entrez Id: 6392
Gene Symbol: SDHD
SDHD 		0.760 CausalMutation disease CLINVAR The R22X mutation of the SDHD gene in hereditary paraganglioma abolishes the enzymatic activity of complex II in the mitochondrial respiratory chain and activates the hypoxia pathway. 11605159 2001
Entrez Id: 6392
Gene Symbol: SDHD
SDHD 		0.760 CausalMutation disease CLINVAR Nearly all hereditary paragangliomas in the Netherlands are caused by two founder mutations in the SDHD gene. 11391798 2001
Entrez Id: 6392
Gene Symbol: SDHD
SDHD 		0.760 CausalMutation disease CLINVAR Novel mutations and the emergence of a common mutation in the SDHD gene causing familial paraganglioma. 11343322 2001
Entrez Id: 6392
Gene Symbol: SDHD
SDHD 		0.760 CausalMutation disease CLINVAR Prevalence of SDHB, SDHC, and SDHD germline mutations in clinic patients with head and neck paragangliomas. 11897817 2002
Entrez Id: 6392
Gene Symbol: SDHD
SDHD 		0.760 CausalMutation disease CLINVAR Germ-line mutations in nonsyndromic pheochromocytoma. 12000816 2002
Entrez Id: 6392
Gene Symbol: SDHD
SDHD 		0.760 CausalMutation disease CLINVAR Identification of novel SDHD mutations in patients with phaeochromocytoma and/or paraganglioma. 12111639 2002
Entrez Id: 6392
Gene Symbol: SDHD
SDHD 		0.760 CausalMutation disease CLINVAR Frequent germ-line succinate dehydrogenase subunit D gene mutations in patients with apparently sporadic parasympathetic paraganglioma. 12114404 2002
Entrez Id: 6392
Gene Symbol: SDHD
SDHD 		0.760 CausalMutation disease CLINVAR A role for mitochondrial enzymes in inherited neoplasia and beyond. 12612654 2003
Entrez Id: 6392
Gene Symbol: SDHD
SDHD 		0.760 CausalMutation disease CLINVAR A novel mutation in the SDHD gene in a family with inherited paragangliomas--implications of genetic diagnosis for follow up and treatment. 12509798 2003
Entrez Id: 6392
Gene Symbol: SDHD
SDHD 		0.760 GeneticVariation disease CLINVAR Altitude is a phenotypic modifier in hereditary paraganglioma type 1: evidence for an oxygen-sensing defect. 12811540 2003