HCG significantly promoted the expression of p-PERK, p-eIF2α, GRP78, CHOP, Bax and cleaved caspase-12 in RCECs (<i>P</i><0.05), while remarkably decreased the expression of Bcl-2 and caspase-12 (<i>P</i><0.05), and the alterations caused by glucose were in concentration- and time-dependent manners.
When corpora lutea of the midluteal phase were incubated with hCG, hCG significantly increased the mRNA and protein levels of Bcl-2 and significantly decreased those of Bax.