Gene: GPAA1 ×
Source: BEFREE ×
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 8733
Gene Symbol: GPAA1
GPAA1 		0.040 GeneticVariation disease BEFREE The aim of this study was to better define the LV geometric changes in FRDA with respect to sex, body size and subject age, and to investigate the relationship of LV changes with genetic severity, as assessed by GAA repeat length within the shorter allele of the FXN gene (GAA1). 31721791 2019
Entrez Id: 8733
Gene Symbol: GPAA1
GPAA1 		0.040 Biomarker disease BEFREE We investigated the effects of FRDA on regional long axis function of the left and right ventricles, and also the relationship of long axis systolic (s`) and early diastolic (e`) peak velocities with GAA repeat number on the shorter (GAA1) and longer FXN alleles (GAA2). 30596685 2018
Entrez Id: 8733
Gene Symbol: GPAA1
GPAA1 		0.040 AlteredExpression disease BEFREE In cFA and LOFA patients mRNA levels correlated directly with protein levels and age at onset, and inversely with GAA1 and GAA2. 21412413 2011
Entrez Id: 8733
Gene Symbol: GPAA1
GPAA1 		0.040 GeneticVariation disease BEFREE The AGTR1 polymorphism rs5186 appears to modify the FRDA cardiac phenotype independently of GAA1. 21771600 2011