| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.180 | GeneticVariation | phenotype | GWASCAT | Genomic and transcriptomic association studies identify 16 novel susceptibility loci for venous thromboembolism. | 31420334 | 2019 | ||||
|
0.180 | Biomarker | phenotype | BEFREE | Elevated D-dimer, FVIII and lupus anticoagulant show promise for predicting recurrent VTE and PTS in children and young adults. | 29078111 | 2017 | ||||
|
0.180 | AlteredExpression | phenotype | BEFREE | Higher FVIII coagulant activity (FVIII :C) and VWF antigen (VWF :Ag) are risk factors for cardiovascular disease and venous thromboembolism. | 25779970 | 2015 | ||||
|
0.180 | Biomarker | phenotype | BEFREE | The results of our study showed that the factor V Leiden mutation and high FVIII are associated with an increased risk of VTE in women with breast cancer during adjuvant tamoxifen. | 25592075 | 2015 | ||||
|
0.180 | GeneticVariation | phenotype | BEFREE | According to our data the LRP1 663C > T polymorphism influences plasma FVIII levels independently of blood group, C-reactive protein and von Willebrand factor and is significantly associated with the risk of VTE. | 17155964 | 2007 | ||||
|
0.180 | AlteredExpression | phenotype | BEFREE | Although thrombotic events are rare in VWD patients receiving repeated infusions of concentrates, there is some concern that sustained high FVIII levels may increase risk of postoperative venous thromboembolism. | 16977571 | 2006 | ||||
|
0.180 | Biomarker | phenotype | BEFREE | More importantly, prevalence of the LRP1 2080D allele was not increased in the group of patients with high FVIII:C and VTE. | 16175004 | 2005 | ||||
|
0.180 | Biomarker | phenotype | LHGDN | High factor VIII (FVIII) levels in venous thromboembolism: role of unbound FVIII. | 15213843 | 2004 | ||||
|
0.180 | Biomarker | phenotype | LHGDN | Co-segregation of thrombophilic disorders in factor V Leiden carriers; the contributions of factor VIII, factor XI, thrombin activatable fibrinolysis inhibitor and lipoprotein(a) to the absolute risk of venous thromboembolism. | 12368162 | 2002 |