Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.360 | GeneticVariation | phenotype | BEFREE | Propensity score-adjusted HRs showed no significant differences in the risk of VTE between tofacitinib-treated and TNF inhibitor-treated patients in either database, with a pooled HR of 1.33 (95% CI 0.78-2.24). | 30552833 | 2019 | ||||
|
0.360 | Biomarker | phenotype | BEFREE | Chemokine C-C motif ligand 3 (CCL3) levels were inversely associated with risk of VTE (hazard ratio [HR] per double increase, 95% confidence interval [CI]: 0.385, 95% CI: 0.161-0.925, <i>p =</i> 0.033), while there was no association between the risk of VTE and serum levels of interleukin (IL)-1β, IL-4, IL-6, IL-8, IL-10, IL-11, tumor necrosis factor (TNF)-α and vascular endothelial growth factor (VEGF), respectively. | 31847343 | 2019 | ||||
|
0.360 | GeneticVariation | phenotype | BEFREE | A promoter 308G/A polymorphism in the tumor necrosis factor-alpha gene has been suggested to modulate the risk for venous thromboembolism. | 26405065 | 2016 | ||||
|
0.360 | GeneticVariation | phenotype | BEFREE | This study aims to investigate the predictive role of five different TNFA gene promoter SNPs, or their haplotype combination(s), for a first VTE episode in gastrointestinal cancer out-patients treated with chemotherapy. | 23852308 | 2013 | ||||
|
0.360 | GeneticVariation | phenotype | BEFREE | Polymorphism G-308A in the promoter of the tumor necrosis factor-α gene and its association with the risk of venous thromboembolism. | 22473048 | 2012 | ||||
|
0.360 | Biomarker | phenotype | CTD_human | Polymorphism G-308A in the promoter of the tumor necrosis factor-α gene and its association with the risk of venous thromboembolism. | 22473048 | 2012 | ||||
|
0.360 | GeneticVariation | phenotype | BEFREE | A common polymorphism in the tumour necrosis factor-alpha gene associated with high TNF levels is not a risk factor for venous thromboembolism. | 9633890 | 1998 |