Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		0.710 Biomarker disease GENOMICS_ENGLAND
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		0.710 Biomarker disease CTD_human
Entrez Id: 6391
Gene Symbol: SDHC
SDHC 		0.300 Biomarker disease CTD_human
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		0.710 GeneticVariation disease CLINVAR 15 YEARS OF PARAGANGLIOMA: Clinical manifestations of paraganglioma syndromes types 1-5. 26273102 2015
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		0.710 CausalMutation disease CLINVAR A case of familial paraganglioma syndrome type 4 caused by a mutation in the SDHB gene. 17143317 2006
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		0.710 CausalMutation disease CLINVAR A comprehensive next generation sequencing-based genetic testing strategy to improve diagnosis of inherited pheochromocytoma and paraganglioma. 23666964 2013
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		0.710 GeneticVariation disease UNIPROT A novel succinate dehydrogenase subunit B gene mutation, H132P, causes familial malignant sympathetic extraadrenal paragangliomas. 14715873 2004
Entrez Id: 7799
Gene Symbol: PRDM2
PRDM2 		0.010 AlteredExpression disease BEFREE A panel of 18 pheochromocytomas (14 benign, and 4 malignant) and 11 abdominal paragangliomas (4 benign, and 7 malignant) were characterised for somatic deletions and mRNA expression status of RIZ1 using loss of heterozygosity (LOH) analysis and real-time quantitative PCR, respectively. 15809732 2005
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		0.710 CausalMutation disease CLINVAR Accumulation of Krebs cycle intermediates and over-expression of HIF1alpha in tumours which result from germline FH and SDH mutations. 15987702 2005
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		0.710 CausalMutation disease CLINVAR Additive effect of nuclear and mitochondrial mutations in a patient with mitochondrial encephalomyopathy. 25736212 2015
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		0.710 Biomarker disease GENOMICS_ENGLAND Advantages and pitfalls of an extended gene panel for investigating complex neurometabolic phenotypes. 27604308 2016
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		0.710 GeneticVariation disease CLINVAR Age-related changes of the ciliary muscle in comparison with changes induced by treatment with prostaglandin F2 alpha. An ultrastructural study in rhesus and cynomolgus monkeys. 2308387 1990
Entrez Id: 6392
Gene Symbol: SDHD
SDHD 		0.020 Biomarker disease BEFREE Among the latter, the PGL1 and PGL4 syndromes are associated with a high risk of multiple localizations. 21617718 2011
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		0.710 CausalMutation disease CLINVAR An apparently sporadic paraganglioma with an SDHB gene germline mutation presenting at age 68 years. 16472267 2006
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		0.710 GeneticVariation disease CLINVAR An immunohistochemical procedure to detect patients with paraganglioma and phaeochromocytoma with germline SDHB, SDHC, or SDHD gene mutations: a retrospective and prospective analysis. 19576851 2009
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		0.710 CausalMutation disease CLINVAR Analysis of SDHAF3 in familial and sporadic pheochromocytoma and paraganglioma. 28738844 2017
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		0.710 CausalMutation disease CLINVAR Association of urinary bladder paragangliomas with germline mutations in the SDHB and VHL genes. 25683602 2015
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		0.710 GeneticVariation disease CLINVAR Biochemically silent abdominal paragangliomas in patients with mutations in the succinate dehydrogenase subunit B gene. 18840642 2008
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		0.710 CausalMutation disease CLINVAR Cardiac Paraganglioma Arising From the Right Atrioventricular Groove in a Paraganglioma-Pheochromocytoma Family Syndrome With Evidence of SDHB Gene Mutation: An Unusual Presentation. 27549546 2016
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		0.710 CausalMutation disease CLINVAR Carney triad versus Carney Stratakis syndrome: two cases which illustrate the difficulty in distinguishing between these conditions in individual patients. 20119652 2010
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		0.710 CausalMutation disease CLINVAR Clinical and molecular genetics of patients with the Carney-Stratakis syndrome and germline mutations of the genes coding for the succinate dehydrogenase subunits SDHB, SDHC, and SDHD. 17667967 2008
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		0.710 CausalMutation disease CLINVAR Clinical exome sequencing for genetic identification of rare Mendelian disorders. 25326637 2014
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		0.710 CausalMutation disease CLINVAR Clinical manifestations of familial paraganglioma and phaeochromocytomas in succinate dehydrogenase B (SDH-B) gene mutation carriers. 18419787 2008
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		0.710 CausalMutation disease CLINVAR Clinical predictors and algorithm for the genetic diagnosis of pheochromocytoma patients. 19825962 2009
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		0.710 GeneticVariation disease CLINVAR Clinical predictors for germline mutations in head and neck paraganglioma patients: cost reduction strategy in genetic diagnostic process as fall-out. 19351833 2009