Gene: CHRNA4 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1137
Gene Symbol: CHRNA4
CHRNA4 		0.020 GeneticVariation disease BEFREE Replication of association of CHRNA4 rare variants with sporadic amyotrophic lateral sclerosis: the Italian multicentre study. 22873564 2012
Entrez Id: 1137
Gene Symbol: CHRNA4
CHRNA4 		0.020 Biomarker disease BEFREE We suggest that these gain-of-function variants might contribute to disease liability in a subset of SALS because Ca(2+) signals mediate nAChR's neuromodulatory effects, including regulation of glutamate release and control of cell survival. 19628475 2009