Entrez Id: |
657 |
Gene Symbol: |
BMPR1A |
BMPR1A
|
0.800 |
Biomarker
|
disease |
MGD |
|
|
|
Entrez Id: |
4089 |
Gene Symbol: |
SMAD4 |
SMAD4
|
0.800 |
Biomarker
|
disease |
CTD_human |
|
|
|
Entrez Id: |
657 |
Gene Symbol: |
BMPR1A |
BMPR1A
|
0.800 |
Biomarker
|
disease |
CTD_human |
|
|
|
Entrez Id: |
324 |
Gene Symbol: |
APC |
APC
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
Familial juvenile polyposis coli with APC gene mutation.
|
9382065 |
1997 |
Entrez Id: |
4089 |
Gene Symbol: |
SMAD4 |
SMAD4
|
0.800 |
Biomarker
|
disease |
CLINGEN |
Targeted deletion of Smad4 shows it is required for transforming growth factor beta and activin signaling in colorectal cancer cells.
|
9482899 |
1998 |
Entrez Id: |
4089 |
Gene Symbol: |
SMAD4 |
SMAD4
|
0.800 |
Biomarker
|
disease |
CLINGEN |
Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes.
|
9506519 |
1998 |
Entrez Id: |
4089 |
Gene Symbol: |
SMAD4 |
SMAD4
|
0.800 |
Biomarker
|
disease |
CLINGEN |
A gene for familial juvenile polyposis maps to chromosome 18q21.1.
|
9545410 |
1998 |
Entrez Id: |
4089 |
Gene Symbol: |
SMAD4 |
SMAD4
|
0.800 |
Biomarker
|
disease |
CLINGEN |
Mutations in the SMAD4/DPC4 gene in juvenile polyposis.
|
9582123 |
1998 |
Entrez Id: |
4089 |
Gene Symbol: |
SMAD4 |
SMAD4
|
0.800 |
Biomarker
|
disease |
MGD |
Gastric and duodenal polyps in Smad4 (Dpc4) knockout mice.
|
10626800 |
1999 |
Entrez Id: |
657 |
Gene Symbol: |
BMPR1A |
BMPR1A
|
0.800 |
Biomarker
|
disease |
CLINGEN |
Germline mutations of the gene encoding bone morphogenetic protein receptor 1A in juvenile polyposis.
|
11381269 |
2001 |
Entrez Id: |
657 |
Gene Symbol: |
BMPR1A |
BMPR1A
|
0.800 |
Biomarker
|
disease |
CLINGEN |
Germline mutations in BMPR1A/ALK3 cause a subset of cases of juvenile polyposis syndrome and of Cowden and Bannayan-Riley-Ruvalcaba syndromes.
|
11536076 |
2001 |
Entrez Id: |
4089 |
Gene Symbol: |
SMAD4 |
SMAD4
|
0.800 |
Biomarker
|
disease |
CLINGEN |
Smad-dependent and Smad-independent pathways in TGF-beta family signalling.
|
14534577 |
2003 |
Entrez Id: |
4089 |
Gene Symbol: |
SMAD4 |
SMAD4
|
0.800 |
Biomarker
|
disease |
CLINGEN |
The prevalence of MADH4 and BMPR1A mutations in juvenile polyposis and absence of BMPR2, BMPR1B, and ACVR1 mutations.
|
15235019 |
2004 |
Entrez Id: |
657 |
Gene Symbol: |
BMPR1A |
BMPR1A
|
0.800 |
Biomarker
|
disease |
CLINGEN |
BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-beta-catenin signaling.
|
15378062 |
2004 |
Entrez Id: |
324 |
Gene Symbol: |
APC |
APC
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
We evaluated beta-catenin and full-length APC protein expression in JPs from children with JPs and JPC.
|
15557107 |
2005 |
Entrez Id: |
1499 |
Gene Symbol: |
CTNNB1 |
CTNNB1
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
We evaluated beta-catenin and full-length APC protein expression in JPs from children with JPs and JPC.
|
15557107 |
2005 |
Entrez Id: |
2022 |
Gene Symbol: |
ENG |
ENG
|
0.500 |
Biomarker
|
disease |
CLINGEN |
Molecular classification of patients with unexplained hamartomatous and hyperplastic polyposis.
|
16287957 |
2005 |
Entrez Id: |
2022 |
Gene Symbol: |
ENG |
ENG
|
0.500 |
GeneticVariation
|
disease |
ORPHANET |
ENG mutations in MADH4/BMPR1A mutation negative patients with juvenile polyposis.
|
17204053 |
2007 |
Entrez Id: |
657 |
Gene Symbol: |
BMPR1A |
BMPR1A
|
0.800 |
Biomarker
|
disease |
CLINGEN |
Cyclooxygenase-2 expression in polyps from a patient with juvenile polyposis syndrome with mutant BMPR1A.
|
17325551 |
2007 |
Entrez Id: |
2022 |
Gene Symbol: |
ENG |
ENG
|
0.500 |
GeneticVariation
|
disease |
ORPHANET |
Large genomic deletions of SMAD4, BMPR1A and PTEN in juvenile polyposis.
|
18178612 |
2008 |
Entrez Id: |
657 |
Gene Symbol: |
BMPR1A |
BMPR1A
|
0.800 |
GermlineCausalMutation
|
disease |
ORPHANET |
The rate of germline mutations and large deletions of SMAD4 and BMPR1A in juvenile polyposis.
|
18823382 |
2009 |
Entrez Id: |
4089 |
Gene Symbol: |
SMAD4 |
SMAD4
|
0.800 |
GermlineCausalMutation
|
disease |
ORPHANET |
The rate of germline mutations and large deletions of SMAD4 and BMPR1A in juvenile polyposis.
|
18823382 |
2009 |
Entrez Id: |
2022 |
Gene Symbol: |
ENG |
ENG
|
0.500 |
Biomarker
|
disease |
CLINGEN |
Prevalence of germline PTEN, BMPR1A, SMAD4, STK11, and ENG mutations in patients with moderate-load colorectal polyps.
|
23399955 |
2013 |
Entrez Id: |
4089 |
Gene Symbol: |
SMAD4 |
SMAD4
|
0.800 |
Biomarker
|
disease |
CLINGEN |
Smad4 acts as tumor suppressor by antagonizing lymphangiogenesis in colorectal cancer.
|
25680269 |
2015 |
Entrez Id: |
107075310 |
Gene Symbol: |
MTCO2P12 |
MTCO2P12
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
COX-2 expression was also significantly higher in the JPC group compared to SRPs.
|
27072264 |
2016 |