Gene: SMAD4 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4 		0.800 Biomarker disease CLINGEN Smad4 acts as tumor suppressor by antagonizing lymphangiogenesis in colorectal cancer. 25680269 2015
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4 		0.800 GermlineCausalMutation disease ORPHANET The rate of germline mutations and large deletions of SMAD4 and BMPR1A in juvenile polyposis. 18823382 2009
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4 		0.800 Biomarker disease CLINGEN The prevalence of MADH4 and BMPR1A mutations in juvenile polyposis and absence of BMPR2, BMPR1B, and ACVR1 mutations. 15235019 2004
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4 		0.800 Biomarker disease CLINGEN Smad-dependent and Smad-independent pathways in TGF-beta family signalling. 14534577 2003
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4 		0.800 Biomarker disease MGD Gastric and duodenal polyps in Smad4 (Dpc4) knockout mice. 10626800 1999
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4 		0.800 Biomarker disease CLINGEN A gene for familial juvenile polyposis maps to chromosome 18q21.1. 9545410 1998
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4 		0.800 Biomarker disease CLINGEN Mutations in the SMAD4/DPC4 gene in juvenile polyposis. 9582123 1998
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4 		0.800 Biomarker disease CLINGEN Targeted deletion of Smad4 shows it is required for transforming growth factor beta and activin signaling in colorectal cancer cells. 9482899 1998
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4 		0.800 Biomarker disease CLINGEN Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes. 9506519 1998
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4 		0.800 Biomarker disease CTD_human