Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 81
Gene Symbol: ACTN4
ACTN4 		0.310 GermlineCausalMutation disease ORPHANET Mutations in ACTN4, encoding alpha-actinin-4, cause familial focal segmental glomerulosclerosis. 10700177 2000
Entrez Id: 81
Gene Symbol: ACTN4
ACTN4 		0.310 GeneticVariation disease BEFREE Haplotype analysis suggests that this FSGS gene is located in a 19-cM region flanked by D1S416 and D1S413, of which 6 cM overlaps with SRN1, suggesting that these distinct clinical subsets of kidney disease may be allelic. 10966492 2000
Entrez Id: 51479
Gene Symbol: ANKFY1
ANKFY1 		0.300 GermlineCausalMutation disease ORPHANET GAPVD1 and ANKFY1 Mutations Implicate RAB5 Regulation in Nephrotic Syndrome. 29959197 2018
Entrez Id: 54443
Gene Symbol: ANLN
ANLN 		0.300 GermlineCausalMutation disease ORPHANET Mutations in the gene that encodes the F-actin binding protein anillin cause FSGS. 24676636 2014
Entrez Id: 8542
Gene Symbol: APOL1
APOL1 		0.300 SusceptibilityMutation disease ORPHANET A role for genetic susceptibility in sporadic focal segmental glomerulosclerosis. 26901816 2016
Entrez Id: 8542
Gene Symbol: APOL1
APOL1 		0.300 SusceptibilityMutation disease ORPHANET A risk allele for focal segmental glomerulosclerosis in African Americans is located within a region containing APOL1 and MYH9. 20668430 2010
Entrez Id: 83478
Gene Symbol: ARHGAP24
ARHGAP24 		0.300 GermlineCausalMutation disease ORPHANET Arhgap24 inactivates Rac1 in mouse podocytes, and a mutant form is associated with familial focal segmental glomerulosclerosis. 21911940 2011
Entrez Id: 396
Gene Symbol: ARHGDIA
ARHGDIA 		0.300 GermlineCausalMutation disease ORPHANET ARHGDIA: a novel gene implicated in nephrotic syndrome. 23434736 2013
Entrez Id: 126859
Gene Symbol: AXDND1
AXDND1 		0.100 CausalMutation disease CLINVAR A molecular genetic analysis of childhood nephrotic syndrome in a cohort of Saudi Arabian families. 23595123 2013
Entrez Id: 126859
Gene Symbol: AXDND1
AXDND1 		0.100 GeneticVariation disease CLINVAR Clinical and epidemiological assessment of steroid-resistant nephrotic syndrome associated with the NPHS2 R229Q variant. 19145239 2009
Entrez Id: 126859
Gene Symbol: AXDND1
AXDND1 		0.100 GeneticVariation disease CLINVAR NPHS2 variation in focal and segmental glomerulosclerosis. 18823551 2008
Entrez Id: 126859
Gene Symbol: AXDND1
AXDND1 		0.100 CausalMutation disease CLINVAR Mutational analysis of the NPHS2 gene in Czech patients with idiopathic nephrotic syndrome. 22578956 2012
Entrez Id: 126859
Gene Symbol: AXDND1
AXDND1 		0.100 GeneticVariation disease CLINVAR NPHS2, encoding the glomerular protein podocin, is mutated in autosomal recessive steroid-resistant nephrotic syndrome. 10742096 2000
Entrez Id: 126859
Gene Symbol: AXDND1
AXDND1 		0.100 CausalMutation disease CLINVAR Patients with mutations in NPHS2 (podocin) do not respond to standard steroid treatment of nephrotic syndrome. 14978175 2004
Entrez Id: 126859
Gene Symbol: AXDND1
AXDND1 		0.100 GeneticVariation disease CLINVAR Screening for NPHS2 mutations may help predict FSGS recurrence after transplantation. 21355056 2011
Entrez Id: 126859
Gene Symbol: AXDND1
AXDND1 		0.100 GeneticVariation disease CLINVAR NPHS2 mutations in late-onset focal segmental glomerulosclerosis: R229Q is a common disease-associated allele. 12464671 2002
Entrez Id: 126859
Gene Symbol: AXDND1
AXDND1 		0.100 GeneticVariation disease CLINVAR Disease-causing missense mutations in NPHS2 gene alter normal nephrin trafficking to the plasma membrane. 15496146 2004
Entrez Id: 126859
Gene Symbol: AXDND1
AXDND1 		0.100 GeneticVariation disease CLINVAR Patients with mutations in NPHS2 (podocin) do not respond to standard steroid treatment of nephrotic syndrome. 14978175 2004
Entrez Id: 126859
Gene Symbol: AXDND1
AXDND1 		0.100 CausalMutation disease CLINVAR Novel mutations in NPHS2 detected in both familial and sporadic steroid-resistant nephrotic syndrome. 11805166 2002
Entrez Id: 126859
Gene Symbol: AXDND1
AXDND1 		0.100 CausalMutation disease CLINVAR NPHS2 mutation associated with recurrence of proteinuria after transplantation. 15015071 2004
Entrez Id: 126859
Gene Symbol: AXDND1
AXDND1 		0.100 GeneticVariation disease CLINVAR Rapid Response to Cyclosporin A and Favorable Renal Outcome in Nongenetic Versus Genetic Steroid-Resistant Nephrotic Syndrome. 26668027 2016
Entrez Id: 126859
Gene Symbol: AXDND1
AXDND1 		0.100 GeneticVariation disease CLINVAR Genetic screening in adolescents with steroid-resistant nephrotic syndrome. 23515051 2013
Entrez Id: 126859
Gene Symbol: AXDND1
AXDND1 		0.100 CausalMutation disease CLINVAR NPHS2 p.V290M mutation in late-onset steroid-resistant nephrotic syndrome. 23242530 2013
Entrez Id: 126859
Gene Symbol: AXDND1
AXDND1 		0.100 CausalMutation disease CLINVAR Plasmapheresis-induced clinical improvement in a patient with steroid-resistant nephrotic syndrome due to podocin (NPHS2) gene mutation. 21171529 2010
Entrez Id: 126859
Gene Symbol: AXDND1
AXDND1 		0.100 CausalMutation disease CLINVAR A spectrum of novel NPHS1 and NPHS2 gene mutations in pediatric nephrotic syndrome patients from Pakistan. 22565185 2012