Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 930
Gene Symbol: CD19
CD19
0.100 Biomarker disease BEFREE We further showed that its occurrence on the most abundant α2-6-disialylated biantennary structure from the peripheral blood mononuclear cells of patients diagnosed as B-cell chronic lymphocytic leukemia varied within ±2-fold abundance from the mean value determined for isolated CD19+ lymphocytes and cultured B-CLL cells. 29087466 2018
Entrez Id: 930
Gene Symbol: CD19
CD19
0.100 Biomarker disease BEFREE Included studies used CD19-directed CAR T-cells for relapsed/refractory B-lineage Acute Lymphoblastic Leukemia and B cell Chronic Lymphocytic Leukemia, enrolled both HSCT-naïve and prior-HSCT patients, and denoted transplant status with outcomes. 30206753 2018
Entrez Id: 930
Gene Symbol: CD19
CD19
0.100 AlteredExpression disease BEFREE We used immunocytochemistry, western blotting, and enzyme-linked immunosorbent assay to show that PTN protein is highly expressed in CD19(+) B cells from B-ALL and B-CLL patients, but barely expressed in B cells from healthy adults. 24698102 2014
Entrez Id: 930
Gene Symbol: CD19
CD19
0.100 Biomarker disease BEFREE We determined the mRNA and protein expression of TIRAP and MyD88 in CD5(+)CD19(+) B-CLL cells and in a subpopulation of normal B CD19(+) lymphocytes. 23419703 2013
Entrez Id: 930
Gene Symbol: CD19
CD19
0.100 Biomarker disease BEFREE We found that miR-29a is up-regulated in indolent human B-CLL as compared with aggressive B-CLL and normal CD19(+) B cells. 20566844 2010
Entrez Id: 930
Gene Symbol: CD19
CD19
0.100 Biomarker disease BEFREE Vaccinated patients showed an increase in B-CLL-reactive T cells followed by a corresponding decline in circulating CD5(+)CD19(+) SP cells. 20072155 2010
Entrez Id: 930
Gene Symbol: CD19
CD19
0.100 Biomarker disease BEFREE Therefore, the present study was conducted to identify suitable reference genes for gene expression studies in CD19(+) B cells isolated from B-CLL patients' peripheral blood. 20813001 2010
Entrez Id: 930
Gene Symbol: CD19
CD19
0.100 AlteredExpression disease BEFREE Though none of the genes were affected by deleterious mutations, we observed a significant down-regulation of NPAT in B-CLL versus CD19+ B cells and of CUL5 in 11q deletion versus non-deletion B-CLL samples and measured reduced PPP2R1B transcript levels in a subset of B-CLL cases. 17449237 2007
Entrez Id: 930
Gene Symbol: CD19
CD19
0.100 AlteredExpression disease BEFREE B-cell chronic lymphocytic leukemia (B-CLL) is phenotypically characterized by cell surface co-expression of CD19, CD20, CD5, and CD23. 15370224 2004
Entrez Id: 930
Gene Symbol: CD19
CD19
0.100 Biomarker disease BEFREE In this study, we used combined CD19-based cell-sorting and fluorescence in situ hybridisation (FISH) to investigate whether or not the BCR-ABL fusion gene was present in the malignant B-cells of a patient who presented a Ph+ CML/B-CLL association. 12802927 2003
Entrez Id: 930
Gene Symbol: CD19
CD19
0.100 AlteredExpression disease BEFREE TRAF1 and to a lesser extent TRAF2 were overexpressed in B-CLL lymphocytes as compared with normal CD19(+) B cells. 12411322 2002
Entrez Id: 930
Gene Symbol: CD19
CD19
0.100 GeneticVariation disease BEFREE A 59-year-old man was diagnosed to have B-cell chronic lymphocytic leukemia with typical morphology and immunophenotype (CD5+, CD19+, and CD23+). 9109943 1997
Entrez Id: 930
Gene Symbol: CD19
CD19
0.100 Biomarker disease BEFREE MDR is constitutively expressed in B-cell chronic lymphocytic leukemia and seems to be related to a CD5/CD19 B-CLL phenotype. 7543067 1995
Entrez Id: 930
Gene Symbol: CD19
CD19
0.100 Biomarker disease BEFREE Evaluation of residual disease in B-cell chronic lymphocytic leukemia patients in clinical and bone-marrow remission using CD5-CD19 markers and PCR study of gene rearrangements. 1282428 1992
Entrez Id: 930
Gene Symbol: CD19
CD19
0.100 Biomarker disease BEFREE We next analysed TGF-beta in highly enriched B lymphocytes from B-CLL (95-100% CD19+), and found that TGF-beta secretion was up to 3 times higher than in the original PBMC population. 1581232 1992