Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2185
Gene Symbol: PTK2B
PTK2B
0.030 Biomarker disease BEFREE Moreover, we also report a role of PYK2 in tumour initiation and invasion-mediated by pure HER2 breast cancer stem-like cells. 31118051 2019
Entrez Id: 2185
Gene Symbol: PTK2B
PTK2B
0.030 AlteredExpression disease BEFREE Trastuzumab treatment increased ADAM10 levels in HER2 positive breast cancer cells (p ≤ 0.001 in BT474; p ≤ 0.01 in SKBR3) and in vivo (p ≤ 0.0001) compared to control, correlating with a decrease in PKB phosphorylation. 24952873 2014
Entrez Id: 2185
Gene Symbol: PTK2B
PTK2B
0.030 PosttranslationalModification disease BEFREE We also investigated the effects of acute and chronic Herceptin treatment on HER3 and PKB phosphorylation in HER2-positive breast cancer cells. 21203579 2010