Gene: PTPN11 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5781
Gene Symbol: PTPN11
PTPN11 		0.030 Biomarker disease BEFREE These findings demonstrate that ErbB2-induced tumors in mice or xenograft tumors induced by transplantation of HER2-amplified BC cells are vulnerable to SHP2 inhibition since it abrogates the expression of the very oncogene that causes of the disease. 30467378 2019
Entrez Id: 5781
Gene Symbol: PTPN11
PTPN11 		0.030 Biomarker disease BEFREE These results indicate that HER2, PTPN11, CCND1 and PIK3CA genes are important biomarkers in HER2+ BC. 30535550 2019
Entrez Id: 5781
Gene Symbol: PTPN11
PTPN11 		0.030 Biomarker disease BEFREE MPZL1 forms a signalling complex with GRB2 adaptor and PTPN11 phosphatase in HER2-positive breast cancer cells. 28912526 2017