Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1387
Gene Symbol: CREBBP
CREBBP 		0.350 CausalMutation disease CGI
Entrez Id: 3716
Gene Symbol: JAK1
JAK1 		0.340 CausalMutation disease CGI
Entrez Id: 2033
Gene Symbol: EP300
EP300 		0.330 CausalMutation disease CGI
Entrez Id: 3718
Gene Symbol: JAK3
JAK3 		0.330 CausalMutation disease CGI
Entrez Id: 3575
Gene Symbol: IL7R
IL7R 		0.320 CausalMutation disease CGI
Entrez Id: 4853
Gene Symbol: NOTCH2
NOTCH2 		0.310 CausalMutation disease CGI
Entrez Id: 1991
Gene Symbol: ELANE
ELANE 		0.110 Biomarker disease HPO
Entrez Id: 2672
Gene Symbol: GFI1
GFI1 		0.110 Biomarker disease HPO
Entrez Id: 699
Gene Symbol: BUB1
BUB1 		0.110 Biomarker disease HPO
Entrez Id: 701
Gene Symbol: BUB1B
BUB1B 		0.100 Biomarker disease HPO
Entrez Id: 9184
Gene Symbol: BUB3
BUB3 		0.100 Biomarker disease HPO
Entrez Id: 9702
Gene Symbol: CEP57
CEP57 		0.100 Biomarker disease HPO
Entrez Id: 10312
Gene Symbol: TCIRG1
TCIRG1 		0.100 Biomarker disease HPO
Entrez Id: 54888
Gene Symbol: NSUN2
NSUN2 		0.100 Biomarker disease HPO
Entrez Id: 9319
Gene Symbol: TRIP13
TRIP13 		0.100 Biomarker disease HPO
Entrez Id: 6729
Gene Symbol: SRP54
SRP54 		0.100 Biomarker disease HPO
Entrez Id: 2322
Gene Symbol: FLT3
FLT3 		0.800 AlteredExpression disease BEFREE <b>Purpose:</b> The FLT3 cell-surface receptor tyrosine kinase (CD135) is expressed in a majority of both acute lymphoid leukemia (ALL) and myeloid leukemia (AML). 28108543 2017
Entrez Id: 613
Gene Symbol: BCR
BCR 		0.500 Biomarker disease BEFREE <i>IKZF1</i> gene defects are associated with inferior treatment outcome in both childhood and adult B-cell precursor acute lymphoblastic leukemia and occur in more than 70% of <i>BCR-ABL1</i>-positive and <i>BCR-ABL1</i>-like cases of acute lymphoblastic leukemia. 29519871 2018
Entrez Id: 100310785
Gene Symbol: ALL1
ALL1 		0.080 Biomarker disease BEFREE 11q23 translocations (t(11q23)) are recurring cytogenetic abnormalities in both acute myeloid leukemia (AML) and acute lymphoblastic leukemia, involving the same gene, ALL1 (or MLL). 9529125 1998
Entrez Id: 4297
Gene Symbol: KMT2A
KMT2A 		0.400 Biomarker disease BEFREE 11q23 translocations (t(11q23)) are recurring cytogenetic abnormalities in both acute myeloid leukemia (AML) and acute lymphoblastic leukemia, involving the same gene, ALL1 (or MLL). 9529125 1998
Entrez Id: 4297
Gene Symbol: KMT2A
KMT2A 		0.400 Biomarker disease BEFREE 11q23/MLL rearrangement confers a poor prognosis in infants with acute lymphoblastic leukemia. 8164041 1994
Entrez Id: 53335
Gene Symbol: BCL11A
BCL11A 		0.010 AlteredExpression disease BEFREE 14q32/miRNA clusters loss of heterozygosity in acute lymphoblastic leukemia is associated with up-regulation of BCL11a. 20578197 2010
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A 		0.040 Biomarker disease BEFREE 5' CpG island hypermethylation is associated with transcriptional silencing of the p21(CIP1/WAF1/SDI1) gene and confers poor prognosis in acute lymphoblastic leukemia. 11895758 2002
Entrez Id: 56996
Gene Symbol: SLC12A9
SLC12A9 		0.010 Biomarker disease BEFREE 5' CpG island hypermethylation is associated with transcriptional silencing of the p21(CIP1/WAF1/SDI1) gene and confers poor prognosis in acute lymphoblastic leukemia. 11895758 2002
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		0.400 GeneticVariation disease BEFREE 5,10-Methylenetetrahydrofolate reductase polymorphisms and acute lymphoblastic leukemia risk: a meta-analysis. 17035405 2006