Gene: AFF1 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4299
Gene Symbol: AFF1
AFF1 		0.080 GeneticVariation disease BEFREE The most common MLL mutation in acute lymphoblastic leukemia is the t(4;11)(q21;q23) chromosome translocation that fuses MLL in-frame with the AF4 gene producing MLL-AF4 and AF4-MLL fusion proteins. 27856324 2017
Entrez Id: 4299
Gene Symbol: AFF1
AFF1 		0.080 Biomarker disease BEFREE In non-DS, frequent abnormalities were MLL rearrangements, mainly MLL-AFF1 in acute lymphoblastic leukemia and MLL-MLLT3 in AML. 24991719 2015
Entrez Id: 4299
Gene Symbol: AFF1
AFF1 		0.080 GeneticVariation disease BEFREE The clinical characteristics, therapy and outcome of 85 adults with acute lymphoblastic leukemia and t(4;11)(q21;q23)/MLL-AFF1 prospectively treated in the UKALLXII/ECOG2993 trial. 23349309 2013
Entrez Id: 4299
Gene Symbol: AFF1
AFF1 		0.080 GeneticVariation disease BEFREE A translocation in acute lymphoblastic leukemia that cytogenetically mimics the recurrent MLL-AFF1 translocation and fuses SEPT11 to MLL. 20633769 2010
Entrez Id: 4299
Gene Symbol: AFF1
AFF1 		0.080 GeneticVariation disease LHGDN Age-related differences in leukemia biology and prognosis: the paradigm of MLL-AF4-positive acute lymphoblastic leukemia. 17301807 2007
Entrez Id: 4299
Gene Symbol: AFF1
AFF1 		0.080 AlteredExpression disease LHGDN The incidence of T-cell receptor gene rearrangements in childhood B-lineage acute lymphoblastic leukemia is related to immunophenotype and fusion oncogene expression. 16386788 2006
Entrez Id: 4299
Gene Symbol: AFF1
AFF1 		0.080 Biomarker disease LHGDN [Detection of fusion genes resulting from chromosome abnormalities in childhood acute lymphoblastic leukemia]. 16215946 2005
Entrez Id: 4299
Gene Symbol: AFF1
AFF1 		0.080 AlteredExpression disease LHGDN B-cell development in the presence of the MLL/AF4 oncoprotein proceeds in the absence of HOX A7 and HOX A9 expression. 14562113 2003