Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6929
Gene Symbol: TCF3
TCF3
0.400 GeneticVariation disease BEFREE t(17;19)(q21-q22;p13), responsible for TCF3-HLF fusion, is a rare translocation in childhood B-cell precursor acute lymphoblastic leukemia(BCP-ALL). t(1;19)(q23;p13), producing TCF3-PBX1 fusion, is a common translocation in childhood BCP-ALL. 31305009 2019
Entrez Id: 6929
Gene Symbol: TCF3
TCF3
0.400 AlteredExpression disease BEFREE We reviewed the roles of miRNA here with emphasis on their function in human leukemia and the mechanisms of the TEL/AML1, BCR/ABL, MLL/AF4 and TCF3/PBX1 oncoproteins on miRNAs expression in acute lymphoblastic leukemia. 27431573 2016
Entrez Id: 6929
Gene Symbol: TCF3
TCF3
0.400 GeneticVariation disease BEFREE Clinical features and prognostic significance of TCF3-PBX1 fusion gene in Chinese children with acute lymphoblastic leukemia by using a modified ALL-BFM-95 protocol. 25551271 2015
Entrez Id: 6929
Gene Symbol: TCF3
TCF3
0.400 Biomarker disease BEFREE Investigation for TCF3(E2A)-PBX1 rearrangements may be useful in BCL6-positive B-lymphoblastic leukemia. 25780007 2015
Entrez Id: 6929
Gene Symbol: TCF3
TCF3
0.400 Biomarker disease CTD_human Genomics and drug profiling of fatal TCF3-HLF-positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options. 26214592 2015
Entrez Id: 6929
Gene Symbol: TCF3
TCF3
0.400 GeneticVariation disease BEFREE This study reviewed the clinical characteristics of 112 pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL) patients with TCF3-PBX1 fusion treated according to the Japan Association of Childhood Leukemia Study (JACLS) ALL02 protocol (n = 82) and Children's Cancer and Leukemia Study Group (CCLSG) ALL 2004 protocol (n = 30). 24578304 2014
Entrez Id: 6929
Gene Symbol: TCF3
TCF3
0.400 Biomarker disease BEFREE Through a novel approach combining gene expression and interactome data analysis, we provide new insight into TCF3-PBX1 and ETV6-RUNX1 acute lymphoblastic leukemia. 25273558 2014
Entrez Id: 6929
Gene Symbol: TCF3
TCF3
0.400 GeneticVariation disease BEFREE A novel TCF3-HLF fusion transcript in acute lymphoblastic leukemia with a t(17;19)(q22;p13). 23181981 2012
Entrez Id: 6929
Gene Symbol: TCF3
TCF3
0.400 AlteredExpression disease BEFREE PAX5 mutations occur frequently in adult B-cell progenitor acute lymphoblastic leukemia and PAX5 haploinsufficiency is associated with BCR-ABL1 and TCF3-PBX1 fusion genes: a GRAALL study. 19587702 2009
Entrez Id: 6929
Gene Symbol: TCF3
TCF3
0.400 AlteredExpression disease LHGDN BCR-ABL, ETV6-RUNX1 and E2A-PBX1: prevalence of the most common acute lymphoblastic leukemia fusion genes in Mexican patients. 18455790 2008
Entrez Id: 6929
Gene Symbol: TCF3
TCF3
0.400 GeneticVariation disease BEFREE Molecular cytogenetic characterization of TCF3 (E2A)/19p13.3 rearrangements in B-cell precursor acute lymphoblastic leukemia. 17311319 2007
Entrez Id: 6929
Gene Symbol: TCF3
TCF3
0.400 GeneticVariation disease LHGDN Molecular cytogenetic characterization of TCF3 (E2A)/19p13.3 rearrangements in B-cell precursor acute lymphoblastic leukemia. 17311319 2007
Entrez Id: 6929
Gene Symbol: TCF3
TCF3
0.400 GeneticVariation disease LHGDN Hypercalcemia in childhood acute lymphoblastic leukemia: frequent implication of parathyroid hormone-related peptide and E2A-HLF from translocation 17;19. 17183364 2007
Entrez Id: 6929
Gene Symbol: TCF3
TCF3
0.400 Biomarker disease BEFREE Incidence and outcome of TCF3-PBX1-positive acute lymphoblastic leukemia in Austrian children. 18024406 2007
Entrez Id: 6929
Gene Symbol: TCF3
TCF3
0.400 Biomarker disease LHGDN [Detection of fusion genes resulting from chromosome abnormalities in childhood acute lymphoblastic leukemia]. 16215946 2005
Entrez Id: 6929
Gene Symbol: TCF3
TCF3
0.400 GeneticVariation disease BEFREE We report that the t(17;19) in acute lymphoblastic leukemia produces a chimeric transcription factor consisting of the amino-terminal portion of HLH proteins E12/E47 (products of the E2A gene) fused to the basic DNA-binding and leucine zipper dimerization motifs of a novel hepatic protein called hepatic leukemia factor (Hlf). 1516826 1992
Entrez Id: 6929
Gene Symbol: TCF3
TCF3
0.400 GeneticVariation disease BEFREE Specific in vitro amplified probe detects the E2A gene rearrangement in the t(1;19) acute lymphoblastic leukemia. 2243503 1990