Gene: ABCB6 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 10058
Gene Symbol: ABCB6
ABCB6 		0.090 Biomarker disease BEFREE This review also focuses on drug resistance by ABC efflux transporters in cancer cells, particularly hepatocellular carcinoma (HCC) and colorectal carcinoma (CRC) cells. 29303075 2019
Entrez Id: 10058
Gene Symbol: ABCB6
ABCB6 		0.090 Biomarker disease BEFREE We identified six mRNAs (DPYSL4, HOMER1, ABCB6, CENPA, CDK1, STMN1) significantly associated with overall survival in the Cox proportional regression model for hepatocellular carcinoma. 31790363 2019
Entrez Id: 10058
Gene Symbol: ABCB6
ABCB6 		0.090 Biomarker disease BEFREE Moreover, C<sub>12</sub>-PRP displayed no cytotoxicity against human liver carcinoma HepG2 and human embryonic kidney HEK-293 cell lines. 29437631 2018
Entrez Id: 10058
Gene Symbol: ABCB6
ABCB6 		0.090 AlteredExpression disease BEFREE We confirmed that ABCB6 mRNA levels were significantly higher in hepatitis C virus (HCV)-related HCCs with early IHR compared to HCV-related HCCs without early IHR (2.5-fold, P=0.01) and the corresponding non-cancerous livers (3.1-fold, P=0.05). 23483087 2013
Entrez Id: 10058
Gene Symbol: ABCB6
ABCB6 		0.090 Biomarker disease BEFREE Correlation analysis between ABC and miRNA expression in individual patients revealed an inverse relationship, providing an indication for miRNA regulation of ABC genes in HCC. 21932399 2012
Entrez Id: 10058
Gene Symbol: ABCB6
ABCB6 		0.090 AlteredExpression disease BEFREE Overexpression of ABC proteins, tyrosine kinases, or both was detectable in 40%, 86% and 33% of HCC samples, respectively. 22110214 2011
Entrez Id: 10058
Gene Symbol: ABCB6
ABCB6 		0.090 AlteredExpression disease BEFREE Increased ABCB6 expression correlated with liver disease progression with the pattern of expression being HCC > cirrhosis > steatosis. 21849266 2011
Entrez Id: 10058
Gene Symbol: ABCB6
ABCB6 		0.090 AlteredExpression disease BEFREE High ATP-binding cassette (ABC) protein expression leads to intrinsic drug resistance of hepatocellular carcinoma (HCC). 21115899 2010
Entrez Id: 10058
Gene Symbol: ABCB6
ABCB6 		0.090 AlteredExpression disease BEFREE The assessment of ABC protein expression pattern may provide important information for the diagnosis and treatment of HCC. 12428063 2002