Further, it is shown that upregulation of DKC1 was necessary for expansion of Glycophorin A+ (GLYA+) erythroblasts and sufficient to extend telomeres in erythroleukemia cells.
Finally, a short hairpin RNA study showed that FUT8 down-regulation induced hemoglobin production and increase of transferrin receptor/glycophorin A-positive cells in human erythroleukemia K562 cells.