Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
0.040 AlteredExpression disease BEFREE We found that Twist and phosphorylated STAT3 levels were promoted by the activated Notch1 receptor in human stomach adenocarcinoma SC-M1, embryonic kidney HEK293 and erythroleukemia K562 cells. 22581828 2012
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
0.040 GeneticVariation disease BEFREE Specifically, five derivative compounds of G6 having structural similarity to the original lead compound were obtained and analyzed for their ability to (i) inhibit Jak2-V617F-mediated cell growth, (ii) inhibit the levels of phospho-Jak2, phospho-STAT3, and phospho-STAT5; (iii) induce apoptosis in human erythroleukemia cells; and (iv) suppress pathologic cell growth of Jak2-V617F-expressing human bone marrow cells ex vivo. 20667821 2010
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
0.040 Biomarker disease BEFREE Stat3 also plays an essential role in leukemic development induced by viral oncogenes, chromosomal translocations and by the Friend erythroleukemia virus. 19482615 2009
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
0.040 Biomarker disease BEFREE Thus, Stat1 and Stat3 may support cell growth in part via c-myc gene activation in primary erythroleukemia cells. 11843291 2002