Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2167
Gene Symbol: FABP4
FABP4 		0.030 AlteredExpression disease BEFREE Childhood obesity is associated with higher FABP4 levels that may promote cardiometabolic risk. 20156355 2010
Entrez Id: 2167
Gene Symbol: FABP4
FABP4 		0.030 AlteredExpression disease BEFREE Childhood obesity and OSA are associated with higher plasma FABP4 levels and thus promote cardiometabolic risk. 21664182 2011
Entrez Id: 811
Gene Symbol: CALR
CALR 		0.010 Biomarker disease BEFREE Obesity in childhood cancer survivors remains associated with previous exposure to CRT and glucocorticoids. 25963547 2015
Entrez Id: 799
Gene Symbol: CALCR
CALCR 		0.010 Biomarker disease BEFREE Obesity in childhood cancer survivors remains associated with previous exposure to CRT and glucocorticoids. 25963547 2015
Entrez Id: 6535
Gene Symbol: SLC6A8
SLC6A8 		0.010 Biomarker disease BEFREE Obesity in childhood cancer survivors remains associated with previous exposure to CRT and glucocorticoids. 25963547 2015
Entrez Id: 3605
Gene Symbol: IL17A
IL17A 		0.020 AlteredExpression disease BEFREE Childhood obesity is an independent factor that is associated with an elevated frequency of circulating T<sub>H</sub>17 cells and higher expression of RORC- and IL-17A-mRNA after <i>in vitro</i> stimulation with Ionomycin. 29201026 2017
Entrez Id: 5346
Gene Symbol: PLIN1
PLIN1 		0.010 Biomarker disease BEFREE Childhood Obesity Risk in Relationship to Perilipin 1 (<i>PLIN1</i>) Gene Regulation by Circulating microRNAs. 31851864 2020
Entrez Id: 4160
Gene Symbol: MC4R
MC4R 		0.100 GeneticVariation disease BEFREE MC4R mutations may be a non-negligible cause of severe obesity in children with variable expression and penetrance. 11487744 2001
Entrez Id: 5465
Gene Symbol: PPARA
PPARA 		0.030 GeneticVariation disease BEFREE PPAR-gamma2 Pro12Ala variant is associated with greater insulin sensitivity in childhood obesity. 15531738 2005
Entrez Id: 5443
Gene Symbol: POMC
POMC 		0.040 GeneticVariation disease BEFREE Proopiomelanocortin (POMC) has been found to be associated with rare Mendelian forms of obesity in children, and, in linkage studies, genomic regions containing the POMC locus have been linked to leptin levels, a predictor of obesity, in white, Mexican-American, and African-American families. 16222047 2005
Entrez Id: 5465
Gene Symbol: PPARA
PPARA 		0.030 GeneticVariation disease BEFREE PPAR-gamma2 Pro12Ala variant, insulin resistance and plasma long-chain polyunsaturated fatty acids in childhood obesity. 16940242 2006
Entrez Id: 84539
Gene Symbol: MCHR2
MCHR2 		0.010 GeneticVariation disease BEFREE MCHR2 maps on chromosome 6q16.3, in a susceptibility locus for childhood obesity. 17698913 2007
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ 		0.100 GeneticVariation disease BEFREE ADIPOQ gene polymorphism rs1501299 interacts with fibre intake to affect adiponectin concentration in children: the GENe-Diet Attica Investigation on childhood obesity. 19543786 2009
Entrez Id: 5468
Gene Symbol: PPARG
PPARG 		0.040 GeneticVariation disease BEFREE Peroxisome proliferator-activated receptor-gamma (PPARgamma) Pro12Ala polymorphism and risk for pediatric obesity. 19634985 2009
Entrez Id: 4160
Gene Symbol: MC4R
MC4R 		0.100 GeneticVariation disease BEFREE Melanocortin-4 receptor gene variants in Chilean families: association with childhood obesity and eating behavior. 20406574 2010
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.020 GeneticVariation disease BEFREE Vascular endothelial growth factor haplotypes associated with childhood obesity. 21612402 2011
Entrez Id: 3481
Gene Symbol: IGF2
IGF2 		0.010 PosttranslationalModification disease BEFREE Insulin-like growth factor 2/H19 methylation at birth and risk of overweight and obesity in children. 22341586 2012
Entrez Id: 7351
Gene Symbol: UCP2
UCP2 		0.020 GeneticVariation disease BEFREE Mitochondrial uncoupling protein 2 (UCP2) gene polymorphisms are associated with childhood obesity and related metabolic disorders. 23314523 2013
Entrez Id: 4160
Gene Symbol: MC4R
MC4R 		0.100 GeneticVariation disease BEFREE MC4R polymorphism rs17782313 may contribute to childhood obesity, affecting enjoyment of food, satiety responsiveness, and possibly eating in the absence of hunger. 24139164 2014
Entrez Id: 6288
Gene Symbol: SAA1
SAA1 		0.010 GeneticVariation disease BEFREE SAA1 gene variants and childhood obesity in China. 24171731 2013
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ 		0.100 GeneticVariation disease BEFREE ADIPOQ -11377C>G Polymorphism Increases the Risk of Adipokine Abnormalities and Child Obesity Regardless of Dietary Intake. 26192702 2016
Entrez Id: 26291
Gene Symbol: FGF21
FGF21 		0.010 Biomarker disease BEFREE FGF21 deficiency is associated with childhood obesity, insulin resistance and hypoadiponectinaemia: The BCAMS Study. 28139438 2017
Entrez Id: 5802
Gene Symbol: PTPRS
PTPRS 		0.010 PosttranslationalModification disease BEFREE PTPRS and PER3 methylation levels are associated with childhood obesity: results from a genome-wide methylation analysis. 28614626 2018
Entrez Id: 5468
Gene Symbol: PPARG
PPARG 		0.040 Biomarker disease BEFREE PPARγ is decreased in childhood obesity and may be responsible for diminished ANGPTL4 levels. 28733963 2018
Entrez Id: 4318
Gene Symbol: MMP9
MMP9 		0.020 Biomarker disease BEFREE Matrix metalloproteinase 9 (MMP9) and acetyl-CoA carboxylase β (ACACB) were identified as hub genes in the PPI network and may therefore be marker genes for child obesity. 28810559 2017