| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.070 | AlteredExpression | disease | BEFREE | And no association of lncRNA ANRIL expression with IL-1β, IL-5, or IL-8 expression was discovered.LncRNA ANRIL expression correlates with increased AR risk, severity, and inflammation, implying that lncRNA ANRIL might be involved in the pathogenesis of AR. | 31096432 | 2019 | ||||
|
0.070 | Biomarker | disease | BEFREE | Ze339, an herbal extract from Petasites hybridus leaves is effective in treatment of allergic rhinitis by inhibition of a local production of IL-8 and eicosanoid LTB<sub>4</sub> in allergen-challenged patients. | 28139053 | 2017 | ||||
|
0.070 | AlteredExpression | disease | BEFREE | The aim of this study was to assess the impact of a single nasal allergen challenge (NAC) on levels of eotaxin and IL-8 and the inflammatory cells in upper and lower airways of allergic rhinitis (AR) patients. | 21703102 | 2011 | ||||
|
0.070 | Biomarker | disease | BEFREE | Using oligonucleotide chip technique HG-U133A2.0 (Affymetrix, Santa Clara, CA) containing 14500 human full-length genes, gene expression profiles of NP tissues from 6 patients with AR-associated NP, mucosal tissues from the inferior nasal concha of 6 AR patients, and mucosal tissues from the inferior nasal concha of 6 patients with normal nasal cavities were assayed, and differentially expressed genes were analyzed, from which 2 genes (CCL20 and IL-8) that were most up-regulated and 2 genes (RGS1 and GPK4) that were most down-regulated were chosen and verified by real-time PCR. | 19027509 | 2009 | ||||
|
0.070 | AlteredExpression | disease | BEFREE | Association of allergic rhinitis with chronic nasal sinusitis further enhanced NF-kappaB activity, and subsequently lead to even stronger expression of IL-6 and IL-8. | 17040605 | 2007 | ||||
|
0.070 | AlteredExpression | disease | BEFREE | Increased levels of bradykinin and IL-8 have been detected within the airways of individuals with active symptoms of allergic rhinitis and asthma. | 12532104 | 2003 | ||||
|
0.070 | AlteredExpression | disease | BEFREE | The IL-8 level in nasal discharge was significantly higher in the chronic sinusitis group than in the allergic rhinitis group. | 8828544 | 1996 |