Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2 		0.500 Biomarker disease CTD_human Hepatic sulfotransferase as a nephropreventing target by suppression of the uremic toxin indoxyl sulfate accumulation in ischemic acute kidney injury. 24958931 2014
Entrez Id: 581
Gene Symbol: BAX
BAX 		0.500 Biomarker disease CTD_human Phenotypic and genotypic assessment of concomitant drug-induced toxic effects in liver, kidney and blood. 20623750 2011
Entrez Id: 3934
Gene Symbol: LCN2
LCN2 		0.500 Biomarker disease CTD_human A Multiplatform Approach for the Discovery of Novel Drug-Induced Kidney Injury Biomarkers. 28885000 2017
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1 		0.500 Therapeutic disease RGD Heme oxygenase 1 modulates thrombomodulin and endothelial protein C receptor levels to attenuate septic kidney injury. 23807243 2013
Entrez Id: 1191
Gene Symbol: CLU
CLU 		0.500 Biomarker disease RGD Tissue Kim-1 and urinary clusterin as early indicators of cisplatin-induced acute kidney injury in rats. 22581811 2012
Entrez Id: 4846
Gene Symbol: NOS3
NOS3 		0.500 Biomarker disease CTD_human Altered expression of endothelin-1 and endothelial nitric oxide synthase in the juxtaglomerular apparatus of rats with HgCl2-induced acute renal failure. 9788586 1998
Entrez Id: 3240
Gene Symbol: HP
HP 		0.500 Biomarker disease CTD_human A Multiplatform Approach for the Discovery of Novel Drug-Induced Kidney Injury Biomarkers. 28885000 2017
Entrez Id: 7099
Gene Symbol: TLR4
TLR4 		0.500 Biomarker disease CTD_human Relevance of megalin receptor injury with nuclear factor-kappa B upregulation in acute kidney injury induced in rats. 29286200 2018
Entrez Id: 5468
Gene Symbol: PPARG
PPARG 		0.500 Therapeutic disease CTD_human Phenotypic and genotypic assessment of concomitant drug-induced toxic effects in liver, kidney and blood. 20623750 2011
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2 		0.500 Therapeutic disease RGD Olmesartan protects against oxidative stress possibly through the Nrf2 signaling pathway and inhibits inflammation in daunorubicin-induced nephrotoxicity in rats. 24291173 2014
Entrez Id: 26762
Gene Symbol: HAVCR1
HAVCR1 		0.500 Biomarker disease CTD_human Repeat oral dose toxicity studies of melamine in rats and monkeys. 23052191 2013
Entrez Id: 26762
Gene Symbol: HAVCR1
HAVCR1 		0.500 Biomarker disease CTD_human Early prediction of polymyxin-induced nephrotoxicity with next-generation urinary kidney injury biomarkers. 24189134 2014
Entrez Id: 581
Gene Symbol: BAX
BAX 		0.500 Therapeutic disease RGD N-acetylcysteine attenuates glycerol-induced acute kidney injury by regulating MAPKs and Bcl-2 family proteins. 20037173 2010
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.500 Therapeutic disease CTD_human Importance of functional EGF receptors in recovery from acute nephrotoxic injury. 14638913 2003
Entrez Id: 3934
Gene Symbol: LCN2
LCN2 		0.500 Biomarker disease CTD_human Neutrophil gelatinase-associated lipocalin production negatively correlates with HK-2 cell impairment: Evaluation of NGAL as a marker of toxicity in HK-2 cells. 27888128 2017
Entrez Id: 5468
Gene Symbol: PPARG
PPARG 		0.500 Biomarker disease CTD_human Involvement of peroxisome proliferator-activated receptor gamma in vitamin D-mediated protection against acute kidney injury in rats. 24011919 2013
Entrez Id: 4353
Gene Symbol: MPO
MPO 		0.500 Biomarker disease CTD_human Phenotypic and genotypic assessment of concomitant drug-induced toxic effects in liver, kidney and blood. 20623750 2011
Entrez Id: 26762
Gene Symbol: HAVCR1
HAVCR1 		0.500 Biomarker disease CTD_human Hepatic sulfotransferase as a nephropreventing target by suppression of the uremic toxin indoxyl sulfate accumulation in ischemic acute kidney injury. 24958931 2014
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1 		0.500 Biomarker disease CTD_human Cisplatin induces Sirt1 in association with histone deacetylation and increased Werner syndrome protein in the kidney. 21416250 2011
Entrez Id: 4878
Gene Symbol: NPPA
NPPA 		0.500 Biomarker disease CTD_human Human atrial natriuretic factor prevents against norepinephrine-induced acute renal failure in the rat. 2948068 1986
Entrez Id: 5468
Gene Symbol: PPARG
PPARG 		0.500 Therapeutic disease CTD_human Involvement of peroxisome proliferator-activated receptor gamma in vitamin D-mediated protection against acute kidney injury in rats. 24011919 2013
Entrez Id: 3934
Gene Symbol: LCN2
LCN2 		0.500 Biomarker disease CTD_human Decrease in urinary creatinine in acute kidney injury influences diagnostic value of urinary biomarker-to-creatinine ratio in rats. 22005293 2011
Entrez Id: 3934
Gene Symbol: LCN2
LCN2 		0.500 Biomarker disease RGD Bilirubin attenuates the renal tubular injury by inhibition of oxidative stress and apoptosis. 23683031 2013
Entrez Id: 4878
Gene Symbol: NPPA
NPPA 		0.500 Biomarker disease CTD_human Renal protective effects and the prevention of contrast-induced nephropathy by atrial natriuretic peptide. 19298916 2009
Entrez Id: 26762
Gene Symbol: HAVCR1
HAVCR1 		0.500 Biomarker disease CTD_human A Multiplatform Approach for the Discovery of Novel Drug-Induced Kidney Injury Biomarkers. 28885000 2017