Gene: BRCA2 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.700 GeneticVariation disease CLINVAR Novel and recurrent BRCA1/BRCA2 mutations in early onset and familial breast and ovarian cancer detected in the Program of Genetic Counseling in Cancer of Valencian Community (eastern Spain). Relationship of family phenotypes with mutation prevalence. 23479189 2013
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.700 GeneticVariation disease CLINVAR Comprehensive prediction of mRNA splicing effects of BRCA1 and BRCA2 variants. 21523855 2011
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.700 GeneticVariation disease CLINVAR Four new cases of double heterozygosity for BRCA1 and BRCA2 gene mutations: clinical, pathological, and family characteristics. 20373018 2010
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.700 GeneticVariation disease CLINVAR Moderate frequency of BRCA1 and BRCA2 germ-line mutations in Scandinavian familial breast cancer. 9150154 1997
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.700 GeneticVariation disease CLINVAR Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing. 26681312 2016
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.700 GeneticVariation disease CLINVAR A review of a multifactorial probability-based model for classification of BRCA1 and BRCA2 variants of uncertain significance (VUS). 21990134 2012
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.700 GeneticVariation disease CLINVAR A high frequency of BRCA mutations in young black women with breast cancer residing in Florida. 26287763 2015
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.700 GeneticVariation disease CLINVAR Prevalence and penetrance of germline BRCA1 and BRCA2 mutations in a population series of 649 women with ovarian cancer. 11179017 2001
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.700 GeneticVariation disease CLINVAR A BRCA2 founder mutation and seven novel deleterious BRCA mutations in southern Chinese women with breast and ovarian cancer. 19353265 2009
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.700 GeneticVariation disease CLINVAR BRCA1 and BRCA2 mutation carriers in the Breast Cancer Family Registry: an open resource for collaborative research. 18704680 2009
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.700 GeneticVariation disease CLINVAR Interlaboratory diagnostic validation of conformation-sensitive capillary electrophoresis for mutation scanning. 20167696 2010
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.700 GeneticVariation disease CLINVAR Inherited predisposition to breast cancer among African American women. 25428789 2015
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.700 GeneticVariation disease CLINVAR BRCA2 is a moderate penetrance gene contributing to young-onset prostate cancer: implications for genetic testing in prostate cancer patients. 21952622 2011
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.700 GeneticVariation disease CLINVAR Clinical and molecular features associated with biallelic mutations in FANCD1/BRCA2. 16825431 2007
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.700 GeneticVariation disease CLINVAR Improving performance of multigene panels for genomic analysis of cancer predisposition. 26845104 2016
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.700 GeneticVariation disease CLINVAR Pathology of familial breast cancer: differences between breast cancers in carriers of BRCA1 or BRCA2 mutations and sporadic cases. Breast Cancer Linkage Consortium. 9167459 1997
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.700 GeneticVariation disease CLINVAR Mutations in BRCA2 and PALB2 in male breast cancer cases from the United States. 20927582 2011
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.700 GeneticVariation disease CLINVAR BRCA2 germ-line mutations are frequent in male breast cancer patients without a family history of the disease. 9537231 1998
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.700 GeneticVariation disease CLINVAR A classification model for BRCA2 DNA binding domain missense variants based on homology-directed repair activity. 23108138 2013
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.700 GeneticVariation disease CLINVAR RNA splicing. The human splicing code reveals new insights into the genetic determinants of disease. 25525159 2015
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.700 GeneticVariation disease CLINVAR New recurrent BRCA1/2 mutations in Polish patients with familial breast/ovarian cancer detected by next generation sequencing. 25948282 2015
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.700 GeneticVariation disease CLINVAR Mutations in 12 genes for inherited ovarian, fallopian tube, and peritoneal carcinoma identified by massively parallel sequencing. 22006311 2011
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.700 GeneticVariation disease CLINVAR """BRCAness"" syndrome in ovarian cancer: a case-control study describing the clinical features and outcome of patients with epithelial ovarian cancer associated with BRCA1 and BRCA2 mutations." 18955455 2008
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.700 GeneticVariation disease CLINVAR Guidelines for splicing analysis in molecular diagnosis derived from a set of 327 combined in silico/in vitro studies on BRCA1 and BRCA2 variants. 22505045 2012
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.700 GeneticVariation disease CLINVAR Germline Variants in Targeted Tumor Sequencing Using Matched Normal DNA. 26556299 2016