Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3949
Gene Symbol: LDLR
LDLR
0.430 Biomarker disease HPO
Entrez Id: 3949
Gene Symbol: LDLR
LDLR
0.430 Biomarker disease BEFREE Here, we demonstrate that adenovirus-mediated overexpression of SIRT1 in the liver of diet-induced insulin-resistant low-density lipoprotein receptor-deficient mice and of genetically obese ob/ob mice attenuates hepatic steatosis and ameliorates systemic insulin resistance. 21321189 2011
Entrez Id: 3949
Gene Symbol: LDLR
LDLR
0.430 Biomarker disease BEFREE Dietary cholesterol exacerbates hepatic steatosis and inflammation in obese LDL receptor-deficient mice. 21690266 2011
Entrez Id: 3949
Gene Symbol: LDLR
LDLR
0.430 Biomarker disease CTD_human Stevia-derived compounds attenuate the toxic effects of ectopic lipid accumulation in the liver of obese mice: a transcriptomic and metabolomic study. 25554529 2015
Entrez Id: 3949
Gene Symbol: LDLR
LDLR
0.430 AlteredExpression disease BEFREE We also report the finding that steatosis abrogates hepatic LDLR expression and increases circulating LDL levels in a PCSK9-dependent manner. 31004037 2019