Gene: XBP1 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7494
Gene Symbol: XBP1
XBP1 		0.360 Biomarker disease BEFREE Reactivation of XBP1s in mice lacking hepatic IRE1α restores COPII-mediated lipoprotein secretion and reverses the fatty liver and hypolipidemia phenotypes. 31123148 2019
Entrez Id: 7494
Gene Symbol: XBP1
XBP1 		0.360 Biomarker disease BEFREE Collectively, we present direct evidence supporting the importance of XBP1 acetylation in ER stress-induced hepatic steatosis. 31541078 2019
Entrez Id: 7494
Gene Symbol: XBP1
XBP1 		0.360 AlteredExpression disease BEFREE Regarding endoplasmic reticulum stress, X-Box binding protein-1 (XBP1) was upregulated in steatosis score ≥ 2 (P = 0.029) and correlated with plasma palmitate (r = 0.34; P = 0.035). 27689765 2017
Entrez Id: 7494
Gene Symbol: XBP1
XBP1 		0.360 Biomarker disease BEFREE Liver histology demonstrated enhanced injury and fibrosis but less steatosis in the HFS-fed Xbp1(-/-) mice. 26472223 2015
Entrez Id: 7494
Gene Symbol: XBP1
XBP1 		0.360 Biomarker disease CTD_human Increased nuclear accumulation of total XBP-1 protein was observed in steatosis and NASH livers. 24097666 2014
Entrez Id: 7494
Gene Symbol: XBP1
XBP1 		0.360 Biomarker disease BEFREE Increased nuclear accumulation of total XBP-1 protein was observed in steatosis and NASH livers. 24097666 2014
Entrez Id: 7494
Gene Symbol: XBP1
XBP1 		0.360 Biomarker disease BEFREE Fibroblast growth factor 21 is regulated by the IRE1α-XBP1 branch of the unfolded protein response and counteracts endoplasmic reticulum stress-induced hepatic steatosis. 25170079 2014