×
Entrez Id:
9927
Gene Symbol:
MFN2
MFN2
0.200
Biomarker
disease
MGD
×
Entrez Id:
9896
Gene Symbol:
FIG4
FIG4
0.200
Biomarker
disease
MGD
Mutation of FIG4 causes neurodegeneration in the pale tremor mouse and patients with CMT4J.
17572665
2007
×
Entrez Id:
1959
Gene Symbol:
EGR2
EGR2
0.200
Biomarker
disease
MGD
Nab proteins are essential for peripheral nervous system myelination.
16136673
2005
×
Entrez Id:
8898
Gene Symbol:
MTMR2
MTMR2
0.200
Biomarker
disease
MGD
An animal model for Charcot-Marie-Tooth disease type 4B1.
16249189
2005
×
Entrez Id:
1778
Gene Symbol:
DYNC1H1
DYNC1H1
0.200
Biomarker
disease
MGD
A novel mouse model carrying a human cytoplasmic dynein mutation shows motor behavior deficits consistent with Charcot-Marie-Tooth type 2O disease.
29379136
2018
×
Entrez Id:
81846
Gene Symbol:
SBF2
SBF2
0.200
Biomarker
disease
MGD
Loss of the inactive myotubularin-related phosphatase Mtmr13 leads to a Charcot-Marie-Tooth 4B2-like peripheral neuropathy in mice.
18349142
2008
×
Entrez Id:
1959
Gene Symbol:
EGR2
EGR2
0.200
Biomarker
disease
MGD
Congenital hypomyelinating neuropathy with lethal conduction failure in mice carrying the Egr2 I268N mutation.
19244508
2009
×
Entrez Id:
4359
Gene Symbol:
MPZ
MPZ
0.200
Biomarker
disease
MGD
Monocyte chemoattractant protein-1 is a pathogenic component in a model for a hereditary peripheral neuropathy.
18326085
2008
×
Entrez Id:
2705
Gene Symbol:
GJB1
GJB1
0.200
Biomarker
disease
MGD
Connexin32-null mice develop demyelinating peripheral neuropathy.
9700485
1998
×
Entrez Id:
4000
Gene Symbol:
LMNA
LMNA
0.200
Biomarker
disease
MGD
Loss of A-type lamin expression compromises nuclear envelope integrity leading to muscular dystrophy.
10579712
1999
×
Entrez Id:
2705
Gene Symbol:
GJB1
GJB1
0.200
Biomarker
disease
MGD
Structural abnormalities and deficient maintenance of peripheral nerve myelin in mice lacking the gap junction protein connexin 32.
9169515
1997
×
Entrez Id:
5376
Gene Symbol:
PMP22
PMP22
0.200
Biomarker
disease
MGD
The formation of peripheral myelin protein 22 aggregates is hindered by the enhancement of autophagy and expression of cytoplasmic chaperones.
17174099
2007
×
Entrez Id:
5376
Gene Symbol:
PMP22
PMP22
0.200
Biomarker
disease
MGD
Impaired proteasome activity and accumulation of ubiquitinated substrates in a hereditary neuropathy model.
15748170
2005
×
Entrez Id:
9990
Gene Symbol:
SLC12A6
SLC12A6
0.200
Biomarker
disease
MGD
The K-Cl cotransporter KCC3 is mutant in a severe peripheral neuropathy associated with agenesis of the corpus callosum.
12368912
2002
×
Entrez Id:
2617
Gene Symbol:
GARS1
GARS1
0.200
Biomarker
disease
MGD
An ENU-induced mutation in mouse glycyl-tRNA synthetase (GARS) causes peripheral sensory and motor phenotypes creating a model of Charcot-Marie-Tooth type 2D peripheral neuropathy.
19470612
2009
×
Entrez Id:
5376
Gene Symbol:
PMP22
PMP22
0.200
Biomarker
disease
MGD
Nerve conduction abnormalities in the trembler-j mouse: a model for Charcot-Marie-Tooth disease type 1A?
15363066
2004
×
Entrez Id:
54332
Gene Symbol:
GDAP1
GDAP1
0.200
Biomarker
disease
MGD
Lack of GDAP1 induces neuronal calcium and mitochondrial defects in a knockout mouse model of charcot-marie-tooth neuropathy.
25860513
2015