Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.700 Biomarker disease GENOMICS_ENGLAND
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.700 GeneticVariation disease CLINVAR
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.700 CausalMutation disease CLINVAR
Entrez Id: 4486
Gene Symbol: MST1R
MST1R
0.310 Biomarker disease CTD_human
Entrez Id: 170712
Gene Symbol: COX7B2
COX7B2
0.300 Biomarker disease GENOMICS_ENGLAND
Entrez Id: 7045
Gene Symbol: TGFBI
TGFBI
0.030 Biomarker disease BEFREE <b>Background:</b> Transforming growth factor-beta-induced (TGFBI) is an exocrine protein, which has been found to be able to promote the development of nasopharyngeal carcinoma, glioma, pancreatic cancer, and other tumors. 31440088 2019
Entrez Id: 811
Gene Symbol: CALR
CALR
0.100 Biomarker disease BEFREE <b>Conclusion</b>: CALR may promote NPC progression and metastasis via involving Stat3 signaling pathway, and can be regarded as an effective potential predictor for progression and prognosis of NPC. 31632490 2019
Entrez Id: 652995
Gene Symbol: UCA1
UCA1
0.030 AlteredExpression disease BEFREE <b>Conclusion</b>: Our study suggests that UCA1 expression was overexpressed in NPC. 31537148 2019
Entrez Id: 1153
Gene Symbol: CIRBP
CIRBP
0.010 AlteredExpression disease BEFREE <b>Conclusion:</b> Collectively, these findings demonstrate that loss of Cirbp expression is correlated with malignant progression and poor prognosis in NPC. 31413636 2019
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
0.070 Biomarker disease BEFREE <b>Conclusion:</b> Our data suggest that ELF-1 plays an oncogenic role in NPC development associated with the CCL2/CCR2 signaling pathway and may therefore be a potential target for NPC therapy. 31289447 2019
Entrez Id: 118738
Gene Symbol: ZNF488
ZNF488
0.010 Biomarker disease BEFREE <b>Conclusion:</b> These results reveal that ZNF488, as an independent prognostic indicator, promotes cell adhesion and proliferation through collagen IV/FAK/AKT/Cyclin D1 pathway in NPC. 31303793 2019
Entrez Id: 595
Gene Symbol: CCND1
CCND1
0.400 Biomarker disease BEFREE <b>Conclusion:</b> These results reveal that ZNF488, as an independent prognostic indicator, promotes cell adhesion and proliferation through collagen IV/FAK/AKT/Cyclin D1 pathway in NPC. 31303793 2019
Entrez Id: 335
Gene Symbol: APOA1
APOA1
0.020 AlteredExpression disease BEFREE <b>Conclusions / Significance:</b> NPC patient with low serum level of pretreatment apoAI might be at risk of distant metastasis. 29556328 2018
Entrez Id: 811
Gene Symbol: CALR
CALR
0.100 Biomarker disease BEFREE <b>Conclusions</b>: CRT is comparable to IMRT alone for elderly patients with locoregionally advanced NPC. 31737097 2019
Entrez Id: 6535
Gene Symbol: SLC6A8
SLC6A8
0.100 Biomarker disease BEFREE <b>Conclusions</b>: CRT is comparable to IMRT alone for elderly patients with locoregionally advanced NPC. 31737097 2019
Entrez Id: 799
Gene Symbol: CALCR
CALCR
0.100 Biomarker disease BEFREE <b>Conclusions</b>: CRT is comparable to IMRT alone for elderly patients with locoregionally advanced NPC. 31737097 2019
Entrez Id: 885
Gene Symbol: CCK
CCK
0.040 Biomarker disease BEFREE <b>Methods:</b> Several assays including cell counting Kit-8 (CCK-8) assays, colony formation, flow cytometry, immunofluorescence, tumor spheres, and mice model were used to detect the biological function of FoxM1 in NPC. 30416986 2018
Entrez Id: 2305
Gene Symbol: FOXM1
FOXM1
0.070 Biomarker disease BEFREE <b>Methods:</b> Several assays including cell counting Kit-8 (CCK-8) assays, colony formation, flow cytometry, immunofluorescence, tumor spheres, and mice model were used to detect the biological function of FoxM1 in NPC. 30416986 2018
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
0.100 AlteredExpression disease BEFREE <b>Methods:</b> We conducted a systematic literature search of PubMed, Embase, and the Cochrane Library for observational studies published until June, 2018 to identify observational studies on the prognostic effect of tissue VEGF expression or serum VEGF level on the survival of NPC. 30430078 2018
Entrez Id: 3223
Gene Symbol: HOXC6
HOXC6
0.020 AlteredExpression disease BEFREE <b>METHODS:</b> We retrospectively examined the HOXC6 expression and Ki-67 index by immunohistochemistry in biopsy specimens from 124 patients with non-metastasized NPC. 28775784 2017
Entrez Id: 108353832
Gene Symbol: CNE-2
CNE-2
0.100 Biomarker disease BEFREE <b>Objective:</b> The purpose of our study is to investigate the role of miR-17-5p in angiogenesis of nasopharyngeal carcinoma and the crosstalk between HUVECs and CNE-2 via exosomes. 31777597 2019
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.020 Biomarker disease BEFREE <b>Objectives</b>: To evaluate the prognostic significance of Adult Comorbidity Evaluation-27 (ACE-27) for elderly patients (age ≥70 years) with locoregionally advanced nasopharyngeal carcinoma (NPC) treated with Intensity-Modulated Radiotherapy (IMRT), with or without chemotherapy. 31737097 2019
Entrez Id: 28
Gene Symbol: ABO
ABO
0.130 Biomarker disease BEFREE <b>Purpose</b>: To identify the association between ABO blood type and the survivals in nasopharyngeal carcinoma patients. 30854139 2019
Entrez Id: 8614
Gene Symbol: STC2
STC2
0.010 AlteredExpression disease BEFREE <b>Purpose:</b> We previously demonstrated that overexpression of STC2 in nasopharyngeal carcinomas (NPC) positively correlates with radiation resistance and tumor metastasis, two major clinical obstacles to the improvement of NPC management. 31372045 2019
Entrez Id: 9314
Gene Symbol: KLF4
KLF4
0.080 AlteredExpression disease BEFREE <b>Result:</b> Our investigation showed that high expression of KLF4 was correlated with poor prognosis in NPC. 31281496 2019