Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1997
Gene Symbol: ELF1
ELF1
0.010 Biomarker disease BEFREE <b>Results:</b> Gain-of-function of ELF-1 in TW01 and TW04 cells promoted NPC cell proliferation, BrdU incorporation, migration, invasion and cisplatin resistance. 31289447 2019
Entrez Id: 84337
Gene Symbol: ELOF1
ELOF1
0.010 Biomarker disease BEFREE <b>Results:</b> Gain-of-function of ELF-1 in TW01 and TW04 cells promoted NPC cell proliferation, BrdU incorporation, migration, invasion and cisplatin resistance. 31289447 2019
Entrez Id: 1943
Gene Symbol: EFNA2
EFNA2
0.010 Biomarker disease BEFREE <b>Results:</b> Gain-of-function of ELF-1 in TW01 and TW04 cells promoted NPC cell proliferation, BrdU incorporation, migration, invasion and cisplatin resistance. 31289447 2019
Entrez Id: 406953
Gene Symbol: MIR18A
MIR18A
0.070 AlteredExpression disease BEFREE <b>Results:</b> The expression levels of TEP miR-34c-3p and miR-18a-5p were significantly higher in NPC patients as compared to healthy subjects. 31114371 2019
Entrez Id: 406919
Gene Symbol: MIR130A
MIR130A
0.020 AlteredExpression disease BEFREE <i>MiR-130a-3p</i> overexpression inhibited NPC cell viability, proliferation, migration, and invasion but promoted cell apoptosis. 28487475 2017
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.100 Biomarker disease BEFREE <i>Materials and Methods</i>: We performed two meta-analyses based on systematic searches of PubMed, EMBASE, the Cochrane Library and SinoMed: comparison 1 (standard therapy plus mAbs vs. standard therapy) and comparison 2 (radiotherapy plus concurrent mAbs vs. concurrent chemoradiotherapy) to explore the treatment value of anti-EGFR mAbs in NPC. 30519357 2018
Entrez Id: 5071
Gene Symbol: PRKN
PRKN
0.020 Biomarker disease BEFREE <i>SHISA3</i> suppressed NPC cell invasion and metastasis <i>in vitro</i> and <i>in vivo</i> by impeding the E3 ubiquitin ligase tripartite motif containing 21 (TRIM21)-mediated ubiquitination and degradation small G protein signaling modulator 1 (SGSM1) and by inhibiting the MAPK pathway activation. 30573520 2019
Entrez Id: 79594
Gene Symbol: MUL1
MUL1
0.010 Biomarker disease BEFREE <i>SHISA3</i> suppressed NPC cell invasion and metastasis <i>in vitro</i> and <i>in vivo</i> by impeding the E3 ubiquitin ligase tripartite motif containing 21 (TRIM21)-mediated ubiquitination and degradation small G protein signaling modulator 1 (SGSM1) and by inhibiting the MAPK pathway activation. 30573520 2019
Entrez Id: 158506
Gene Symbol: CBLL2
CBLL2
0.010 Biomarker disease BEFREE <i>SHISA3</i> suppressed NPC cell invasion and metastasis <i>in vitro</i> and <i>in vivo</i> by impeding the E3 ubiquitin ligase tripartite motif containing 21 (TRIM21)-mediated ubiquitination and degradation small G protein signaling modulator 1 (SGSM1) and by inhibiting the MAPK pathway activation. 30573520 2019
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1
0.100 Biomarker disease BEFREE <sup>18</sup>FDG PET/PET-CT is superior to BS for diagnosing bone metastases in nasopharyngeal cancer patients.<sup>18</sup>FDG PET/PET-CT may enhance the diagnosis of bone metastases and provide more accurate information for the optimal management of nasopharyngeal cancer. 28938677 2017
Entrez Id: 2321
Gene Symbol: FLT1
FLT1
0.020 Biomarker disease BEFREE <sup>18</sup>F-FLT and <sup>18</sup>F-FDG PET/CT in Predicting Response to Chemoradiotherapy in Nasopharyngeal Carcinoma: Preliminary Results. 28091565 2017
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1
0.100 Biomarker disease BEFREE <sup>18</sup>F-FDG PET/CT-positive CLNs could reasonably be categorized as high-risk clinical tumor volume in IMRT planning for NPC. 29187888 2017
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1
0.100 Biomarker disease BEFREE <sup>18</sup>F-FLT and <sup>18</sup>F-FDG PET/CT in Predicting Response to Chemoradiotherapy in Nasopharyngeal Carcinoma: Preliminary Results. 28091565 2017
Entrez Id: 6387
Gene Symbol: CXCL12
CXCL12
0.030 AlteredExpression disease BEFREE (b) High expression of SDF-1 was observed in advanced NPC (N stage, p < 0.05). 18087217 2007
Entrez Id: 5698
Gene Symbol: PSMB9
PSMB9
0.100 AlteredExpression disease BEFREE 2) and protein 2 (LMP2), in addition small non-polyadenylated viral RNAs non-coding nuclear RNAs (EBERs) and BamHI-A rightward transcripts (BARTs) expressed in NPC tumor cells. 18087217 2007
Entrez Id: 10112
Gene Symbol: KIF20A
KIF20A
0.010 AlteredExpression disease BEFREE 45/105 (42.9%) of NPC specimens expressed high levels of KIF20A among the KIF20A detectable cases. 28081138 2017
Entrez Id: 7476
Gene Symbol: WNT7A
WNT7A
0.010 AlteredExpression disease BEFREE 5'-aza-2' deoxycytidine treatment restored the expression of ITGA9 and WNT7A in two NPC cell lines. 26372814 2015
Entrez Id: 6850
Gene Symbol: SYK
SYK
0.020 PosttranslationalModification disease BEFREE 5-aza-CdR induces the demethylation of Syk promoter in nasopharyngeal carcinoma cell. 23036706 2012
Entrez Id: 9260
Gene Symbol: PDLIM7
PDLIM7
0.100 Biomarker disease BEFREE Nasopharyngeal carcinoma (NPC) is notorious for the metastases, which are in close association with Epstein-Barr virus-encoded latent membrane protein 1 (LMP1). 16648906 2006
Entrez Id: 1890
Gene Symbol: TYMP
TYMP
0.020 AlteredExpression disease BEFREE NPC cells expressing high TP were more sensitive to treatment with the TP-targeting drug, 5'-DFUR. 18559600 2008
Entrez Id: 9997
Gene Symbol: SCO2
SCO2
0.020 AlteredExpression disease BEFREE NPC cells expressing high TP were more sensitive to treatment with the TP-targeting drug, 5'-DFUR. 18559600 2008
Entrez Id: 51754
Gene Symbol: TMEM8B
TMEM8B
0.100 Biomarker disease BEFREE Nasopharyngeal carcinoma-associated gene 6 (NGX6) is a novel candidate suppressor gene of tumor metastasis, which is down-regulated in CRC. 19499154 2009
Entrez Id: 2067
Gene Symbol: ERCC1
ERCC1
0.400 GeneticVariation disease BEFREE Nasopharyngeal carcinoma (NPC) is a platinum-sensitive cancer and excision repair cross-complementing group 1 (ERCC1) polymorphisms have been shown to predict survival in several cancers following platinum therapy. 19549713 2009
Entrez Id: 51754
Gene Symbol: TMEM8B
TMEM8B
0.100 Biomarker disease BEFREE Nasopharyngeal carcinoma associated gene 6 (NGX6) is down-regulated in most colon cancer cell lines and tumor tissues when compared with their normal tissue samples. 20423473 2010
Entrez Id: 51754
Gene Symbol: TMEM8B
TMEM8B
0.100 Biomarker disease BEFREE Nasopharyngeal carcinoma-associated gene 6 (NGX6) is a novel candidate suppressor gene of tumor metastasis, which is down-regulated in colon cancer. 20705583 2010