|
LOC108004545
|
0.100 |
Biomarker
|
disease |
BEFREE |
The therapeutic efficacy of SS and SLN against cancer stem cells was determined by orally administering the drugs to mice bearing CNE1 and CNE2 nasopharyngeal carcinoma xenografts and then evaluating CD133 cell proportions and tumorsphere formation.
|
30239423 |
2019 |
|
LOC108004545
|
0.100 |
Biomarker
|
disease |
BEFREE |
Overexpression of miR-29 causes decrease in the viability of CNE2 nasopharyngeal cancer cells via induction of apoptosis and autophagy.
|
31298371 |
2019 |
|
LOC108004545
|
0.100 |
Biomarker
|
disease |
BEFREE |
We selected NPC sublines CNE2 with stably transfecting empty plasmid (negative control, NC) and short hair RNA (shRNA) plasmid targeting ZBTB7A as research objectives.
|
31309112 |
2019 |
|
LOC108004545
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
The influence of icaritin on the proliferation, migration, and invasion of human nasopharyngeal carcinoma cell CNE2 and the influencing mechanisms were discussed.
|
31739838 |
2019 |
|
LOC108004545
|
0.100 |
Biomarker
|
disease |
BEFREE |
NCSCs were enriched from human nasopharyngeal cancer cell lines CNE2 and HONE1 through tumorsphere-forming assay.
|
31342620 |
2019 |
|
LOC108004545
|
0.100 |
Biomarker
|
disease |
BEFREE |
Herein, the results revealed that isoliquiritigenin could inhibit cell proliferation in nasopharyngeal carcinoma cell lines, including C666-1 and CNE2, in both Cell Counting Kit-8 (CCK-8) and 5-Ethynyl-2'-deoxyuridine (EdU) assay.
|
31004603 |
2019 |
|
LOC108004545
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
We used immunohistochemical (IHC) and western blot methods to evaluate PPAR-<i>γ</i> and E2F2 expression and function in nonkeratinizing NPC and nasopharyngitis (NPG) tissue samples, as well as western blotting and CCK8 analyses in the NPC cell lines, CNE1 and CNE2.
|
31467515 |
2019 |
|
LOC108004545
|
0.100 |
Biomarker
|
disease |
BEFREE |
The DCs were cocultured with T lymphocytes and then acted on the EBV<sup>+</sup> CNE2 nasopharyngeal carcinoma cells.
|
29900557 |
2018 |
|
LOC108004545
|
0.100 |
Biomarker
|
disease |
BEFREE |
The chemoresistant NPC cell lines CNE1DDP and CNE2DDP were resistant to 1 mg/L cisplatin, had resistant indexes of 4.58 and 2.63, respectively, and clearly grew more slowly than the NPC cell lines CNE1 and CNE2.
|
30067426 |
2018 |
|
LOC108004545
|
0.100 |
Biomarker
|
disease |
BEFREE |
This study attempted at understanding the effect of siRNA-RPN2 treatment on the migration and invasion of NPC cell lines CNE2 and HNE1.
|
29942140 |
2018 |
|
LOC108004545
|
0.100 |
Biomarker
|
disease |
BEFREE |
Results demonstrated that combining API and CET could better suppress the viability of the human nasopharyngeal carcinoma cell lines (HONE1 and CNE2) and inhibit the growth of NPC than API or CET used alone.
|
29604587 |
2018 |
|
LOC108004545
|
0.100 |
Biomarker
|
disease |
BEFREE |
The level of ZBTB7A was effectively knocked down by stable transfection of short hair RNA plasmid in NPC cell lines CNE2 and 5-8F (shRNA-CNE2 and shRNA-5-8F), compared with the cells that stably transfected empty plasmid (NC-CNE2 and NC-5-8F).
|
29699474 |
2018 |
|
LOC108004545
|
0.100 |
Biomarker
|
disease |
BEFREE |
Snail-mediated cancer stem cell-like phenotype in human CNE2 nasopharyngeal carcinoma cell.
|
29024225 |
2018 |
|
LOC108004545
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Knockdown of MAPK15, one up-regulated protein kinase in CNE2-IR cells, significantly impaired clonogenic survival, decreased cell viability and increased cell apoptosis following exposure to irradiation, while over-expression of MAPK15 promoted cell survival, induced radioresistance and reduced apoptosis in NPC cell lines CNE1, CNE2, and HONE1.
|
30524968 |
2018 |
|
LOC108004545
|
0.100 |
Biomarker
|
disease |
BEFREE |
We found that curcumin inhibited cell growth, induced apoptosis, retarded cell migration and invasion, and triggered cell cycle arrest in the human nasopharyngeal carcinoma cell lines CNE1 and CNE2.
|
28496336 |
2017 |
|
LOC108004545
|
0.100 |
Biomarker
|
disease |
BEFREE |
The results from two NPC cell lines (CNE1 and CNE2) revealed that the silencing of GnT-V enhanced cetuximab-induced radiosensitivity by decreasing the β-1-6 branching of oligosaccharides on the EGFR.
|
28535302 |
2017 |
|
LOC108004545
|
0.100 |
Biomarker
|
disease |
BEFREE |
After 5-aza-2-deoxycytidine treatment, parkin mRNA expression was restored in CNE1 and CNE2; 92.59% (50/54) of nasopharyngeal carcinoma demonstrated genomic instability.
|
28351314 |
2017 |
|
LOC108004545
|
0.100 |
Biomarker
|
disease |
BEFREE |
By the way, the NPC-derived exosomes come from and CNE2-derived exosomes are enriched in PFKFB3.
|
29151977 |
2017 |
|
LOC108004545
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Epigallocatechin-3-gallate Modulates MicroRNA Expression Profiles in Human Nasopharyngeal Carcinoma CNE2 Cells.
|
28051030 |
2017 |
|
LOC108004545
|
0.100 |
Biomarker
|
disease |
BEFREE |
In this study, we showed that MGCD effectively restored histone acetylation, suppressed cell growth and induced apoptosis in two-dimensional (2D) and three-dimensional (3D) cultured CNE1 and CNE2 nasopharyngeal carcinoma (NPC) cells.
|
27283770 |
2016 |
|
LOC108004545
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Furthermore, functions of the survivin gene in the CNE2 nasopharyngeal carcinoma cell line were assessed.
|
25824761 |
2015 |
|
LOC108004545
|
0.100 |
Biomarker
|
disease |
BEFREE |
In vitro, knockdown of FoxC1 in the CNE2 human NPC cell line by small interfering RNA downregulated vimentin, fibronectin and N‑cadherin expression and reduced the migratory and invasive capacity of CNE2 cells.
|
26461269 |
2015 |
|
LOC108004545
|
0.100 |
Biomarker
|
disease |
BEFREE |
In this report, we silenced Sorcin in human NPC CNE2/DDP cells, and explored the role of Sorcin in MDR reversal.
|
24376145 |
2014 |
|
LOC108004545
|
0.100 |
Biomarker
|
disease |
BEFREE |
In NPC cell lines (CNE1 and CNE2), ectopic LMP1 significantly increased the mRNA and protein levels of eIF4E and the transcriptional activity of the eIF4E promoter in a LMP1-plasmid-transfected dose-dependent manner.
|
24814906 |
2014 |
|
LOC108004545
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Mangiferin induces apoptosis by regulating Bcl-2 and Bax expression in the CNE2 nasopharyngeal carcinoma cell line.
|
25227792 |
2014 |