Gene: HLA-B ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B 		0.180 GeneticVariation disease BEFREE A novel allelic variant in HLA-B*40 lineage, HLA-B*40:298:02, has been identified in an individual of Han ethnicity afflicted with nasopharyngeal carcinoma in Hunan province, southern China. 29676515 2018
Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B 		0.180 GeneticVariation disease BEFREE Another novel variant, Glu-45 in HLA-B pocket B, conferred a protective effect on NPC susceptibility (OR = 0.64, P = 5.23 × 10<sup>-8</sup> ). 30378292 2018
Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B 		0.180 GeneticVariation disease GWASDB A genome-wide association study of nasopharyngeal carcinoma identifies three new susceptibility loci. 20512145 2010
Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B 		0.180 GeneticVariation disease BEFREE HLA-A(*)0206, HLA-B(*)3802 alleles plus the A(*)0207-B(*)4601 and A(*)3303-B(*)5801 haplotypes conferred high risk for NPC showing a combined odds ratio (OR) of 2.6 (P<0.0001). 20072141 2010
Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B 		0.180 Biomarker disease BEFREE Conversely, carriers of HLA-B*4601 in the absence of HLA-A*0207 had a 50% reduction in NPC risk (95% CI = 0.27-0.93). 19683024 2009
Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B 		0.180 GeneticVariation disease BEFREE We determined the frequencies of 17 human leukocyte antigens (HLA), HLA-A and HLA-B, alleles in 88 Malaysian Chinese with NPC. 17609824 2007
Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B 		0.180 GeneticVariation disease BEFREE Previous studies have identified several HLA-B specificities that are associated with nasopharyngeal carcinoma (NPC) in populations of Chinese descent, in particular HLA-B35, -B38, -B46, and -B58. 16547745 2006
Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B 		0.180 Biomarker disease BEFREE HLA-B frequencies in 54 unrelated nasopharyngeal carcinoma (NPC) patients and 49 healthy random controls in Thailand were investigated by direct DNA sequencing. 12074714 2002
Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B 		0.180 GeneticVariation disease BEFREE Individuals with HLA-B*4601, which is in linkage disequilibrium with HLA-A*0207, had an increased risk for NPC (OR = 1.8, 95% CI = 1.2 to 2.5) as did individuals with HLA-A*0207 and HLA-B*4601 (OR = 2.8, 95% CI = 1.7 to 4.4). 12464650 2002