Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4318
Gene Symbol: MMP9
MMP9 		0.500 Therapeutic disease RGD Cariporide, a specific Na/H(+) exchanger 1 blocker, inhibits neointimal proliferation induced by advanced glycation end products in a balloon injury rat model. 23344254 2013
Entrez Id: 4313
Gene Symbol: MMP2
MMP2 		0.500 Therapeutic disease RGD Cariporide, a specific Na/H(+) exchanger 1 blocker, inhibits neointimal proliferation induced by advanced glycation end products in a balloon injury rat model. 23344254 2013
Entrez Id: 4318
Gene Symbol: MMP9
MMP9 		0.500 Biomarker disease CTD_human Carvedilol, a pharmacological antioxidant, inhibits neointimal matrix metalloproteinase-2 and -9 in experimental atherosclerosis. 17964422 2007
Entrez Id: 4313
Gene Symbol: MMP2
MMP2 		0.500 Biomarker disease CTD_human Carvedilol, a pharmacological antioxidant, inhibits neointimal matrix metalloproteinase-2 and -9 in experimental atherosclerosis. 17964422 2007
Entrez Id: 688
Gene Symbol: KLF5
KLF5 		0.500 Biomarker disease CTD_human Synthetic retinoid Am80 suppresses smooth muscle phenotypic modulation and in-stent neointima formation by inhibiting KLF5. 16224062 2005
Entrez Id: 688
Gene Symbol: KLF5
KLF5 		0.500 Biomarker disease RGD BTEB2, a Krüppel-like transcription factor, regulates expression of the SMemb/Nonmuscle myosin heavy chain B (SMemb/NMHC-B) gene. 10417400 1999
Entrez Id: 1901
Gene Symbol: S1PR1
S1PR1 		0.300 Biomarker disease CTD_human Angiotensin II facilitates neointimal formation by increasing vascular smooth muscle cell migration: Involvement of APE/Ref-1-mediated overexpression of sphingosine-1-phosphate receptor 1. 29609002 2018
Entrez Id: 183
Gene Symbol: AGT
AGT 		0.300 Biomarker disease CTD_human Angiotensin II facilitates neointimal formation by increasing vascular smooth muscle cell migration: Involvement of APE/Ref-1-mediated overexpression of sphingosine-1-phosphate receptor 1. 29609002 2018
Entrez Id: 538
Gene Symbol: ATP7A
ATP7A 		0.300 Biomarker disease CTD_human Unexpected role of the copper transporter ATP7A in PDGF-induced vascular smooth muscle cell migration. 20671235 2010
Entrez Id: 183
Gene Symbol: AGT
AGT 		0.300 Biomarker disease CTD_human Cuff-induced vascular intima thickening is influenced by titration of the Ace gene in mice. 19258495 2009
Entrez Id: 1815
Gene Symbol: DRD4
DRD4 		0.200 Therapeutic disease RGD Dopamine D₄ receptors inhibit proliferation and migration of vascular smooth muscle cells induced by insulin via down-regulation of insulin receptor expression. 24888351 2014
Entrez Id: 8678
Gene Symbol: BECN1
BECN1 		0.200 Biomarker disease RGD Beclin 1 knockdown retards re-endothelialization and exacerbates neointimal formation via a crosstalk between autophagy and apoptosis. 25238224 2014
Entrez Id: 2185
Gene Symbol: PTK2B
PTK2B 		0.200 Biomarker disease RGD Novel role of proline-rich nonreceptor tyrosine kinase 2 in vascular wall remodeling after balloon injury. 22922962 2012
Entrez Id: 4835
Gene Symbol: NQO2
NQO2 		0.200 Biomarker disease RGD Downregulation of quinone reductase 2 attenuates vascular smooth muscle cells proliferation and neointimal formation in balloon injured rat carotid artery. 22508052 2012
Entrez Id: 2321
Gene Symbol: FLT1
FLT1 		0.200 Therapeutic disease RGD Vascular endothelial growth factor-induced osteopontin expression mediates vascular inflammation and neointima formation via Flt-1 in adventitial fibroblasts. 22814749 2012
Entrez Id: 5058
Gene Symbol: PAK1
PAK1 		0.200 Biomarker disease RGD Novel role of proline-rich nonreceptor tyrosine kinase 2 in vascular wall remodeling after balloon injury. 22922962 2012
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1 		0.200 Therapeutic disease RGD Heme oxygenase-1 inhibition prevents intimal hyperplasia enhancing nitric oxide-dependent apoptosis of vascular smooth muscle cells. 21804207 2011
Entrez Id: 2152
Gene Symbol: F3
F3 		0.200 Therapeutic disease RGD Peroxisome proliferator-activated receptor-gamma agonists suppress tissue factor overexpression in rat balloon injury model with paclitaxel infusion. 22140576 2011
Entrez Id: 54434
Gene Symbol: SSH1
SSH1 		0.200 Biomarker disease RGD Slingshot isoform-specific regulation of cofilin-mediated vascular smooth muscle cell migration and neointima formation. 21868701 2011
Entrez Id: 7035
Gene Symbol: TFPI
TFPI 		0.200 Therapeutic disease RGD Peroxisome proliferator-activated receptor-gamma agonists suppress tissue factor overexpression in rat balloon injury model with paclitaxel infusion. 22140576 2011
Entrez Id: 1536
Gene Symbol: CYBB
CYBB 		0.200 Therapeutic disease RGD Local arterial nanoparticle delivery of siRNA for NOX2 knockdown to prevent restenosis in an atherosclerotic rat model. 20485380 2010
Entrez Id: 7528
Gene Symbol: YY1
YY1 		0.200 Therapeutic disease RGD Interplay between heme oxygenase-1 and the multifunctional transcription factor yin yang 1 in the inhibition of intimal hyperplasia. 21030713 2010
Entrez Id: 5058
Gene Symbol: PAK1
PAK1 		0.200 Biomarker disease RGD A role for Gab1/SHP2 in thrombin activation of PAK1: gene transfer of kinase-dead PAK1 inhibits injury-induced restenosis. 19359598 2009
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1 		0.200 Therapeutic disease RGD A DNA enzyme against plasminogen activator inhibitor- type 1 (PAI-1) limits neointima formation after angioplasty in an obese diabetic rodent model. 18091579 2007
Entrez Id: 3084
Gene Symbol: NRG1
NRG1 		0.200 Biomarker disease RGD Neuregulin-1 attenuates neointimal formation following vascular injury and inhibits the proliferation of vascular smooth muscle cells. 17438359 2007