Gene: EDN1 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1906
Gene Symbol: EDN1
EDN1 		0.330 Biomarker phenotype BEFREE Our results suggest that TRPA1 acts as a molecular target for ET-1, and sensitization of TRPA1 through ET<sub>A</sub>R-PKA pathway contributes to ET-1-induced mechanical hyperalgesia. 30990108 2020
Entrez Id: 1906
Gene Symbol: EDN1
EDN1 		0.330 Biomarker phenotype BEFREE In naive rats, submucosal injection of endothelin-1 caused mechanical allodynia that was sensitive to HC-030031 and SB-366791 but not to RN-1734. 29518348 2018
Entrez Id: 1906
Gene Symbol: EDN1
EDN1 		0.330 Biomarker phenotype BEFREE In the present study, we applied an intradermal ET-1 sensitization model to induce mechanical hyperalgesia in healthy subjects. 24151613 2013
Entrez Id: 1906
Gene Symbol: EDN1
EDN1 		0.330 Biomarker phenotype CTD_human Role of ET(A) and ET(B) endothelin receptors on endothelin-1-induced potentiation of nociceptive and thermal hyperalgesic responses evoked by capsaicin in rats. 19429182 2009