Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2670
Gene Symbol: GFAP
GFAP
0.370 AlteredExpression phenotype BEFREE Moreover, the intrathecal administration of JNK inhibitors SP600125 reduced the expression of glial fibrillary acidic protein, while microinjection of the SP600125 decreased the mechanical allodynia of CIBP rats. 30700204 2019
Entrez Id: 2670
Gene Symbol: GFAP
GFAP
0.370 AlteredExpression phenotype BEFREE Systemic injection of paclitaxel resulted in increased expression of glial fibrillary acidic protein (a common marker of astrocytic activation), as well as both systemic or intrathecal injection of paclitaxel induced pain hypersensitivity indicated by the development of mechanical allodynia, which was significantly reversed by the astrocytic inhibitor L-α-AA. 31707979 2019
Entrez Id: 2670
Gene Symbol: GFAP
GFAP
0.370 AlteredExpression phenotype BEFREE Intrathecal MaR1 significantly attenuated mechanical allodynia and thermal hyperalgesia from day 5 to day 7 post-SNL, which was associated with decreased spinal levels of glial markers, GFAP and IBA1. 30127635 2018
Entrez Id: 2670
Gene Symbol: GFAP
GFAP
0.370 Biomarker phenotype BEFREE We found that the characters of BCP were mimicked by intra-femural inoculation of LLC cells in mice, and the expressions of Cx43, GFAP and p-NR2B in BCP mice were remarkably increased in a time-dependent manner from day 7 to day 21 after cell inoculation with a gradual aggravate in spontaneous pain and mechanical allodynia. 29867362 2018
Entrez Id: 2670
Gene Symbol: GFAP
GFAP
0.370 Biomarker phenotype BEFREE T-cell-deficient (Rag1<sup>-/-</sup>) mice significantly attenuated MA-induced mechanical allodynia and GFAP upregulation. 29311654 2018
Entrez Id: 2670
Gene Symbol: GFAP
GFAP
0.370 AlteredExpression phenotype BEFREE Finally, co-administration of carbenoxolone (CBX; a GJ decoupler) or Gap26 (a specific Cx43 mimetic blocking peptide) with IL-1ra significantly blocked the IL-1ra-induced early development of contralateral MA and the associated upregulation of spinal Cx43 and GFAP expression. 27776252 2017
Entrez Id: 2670
Gene Symbol: GFAP
GFAP
0.370 Biomarker phenotype BEFREE We have shown for the first time that i.v. administration of substance P attenuated mechanical allodynia in the maintenance phase of neuropathic pain using von Frey's test, and simultaneously reduced levels of phospho-ERK and GFAP, which are representative biochemical markers of neuropathic pain. 27956715 2017
Entrez Id: 2670
Gene Symbol: GFAP
GFAP
0.370 Biomarker phenotype CTD_human Resveratrol suppresses glial activation and alleviates trigeminal neuralgia via activation of AMPK. 27093858 2016