Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
0.330 GeneticVariation phenotype BEFREE Collectively these data suggest that spinal P450c17 activates astrocytes via p38 phosphorylation, ultimately leading to the development of mechanical allodynia in a model of peripheral neuropathy. 31387001 2019
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
0.330 AlteredExpression phenotype BEFREE The ERK inhibitor U0126 alleviated mechanical allodynia with lower p-ERK expression in the sham females but did not affect the OVX rats. 30816240 2019
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
0.330 Biomarker phenotype BEFREE Repeated intrathecal application of the specific p38 MAPK inhibitor SB203580 reduced CFA-induced mechanical allodynia as well. 30442166 2018
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
0.330 Biomarker phenotype CTD_human Resveratrol suppresses glial activation and alleviates trigeminal neuralgia via activation of AMPK. 27093858 2016
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
0.330 Biomarker phenotype CTD_human Extracellular signaling-regulated kinase-1 and -2 (ERK 1/2) mediate referred hyperalgesia in a murine model of visceral pain. 12941468 2003