Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 729230
Gene Symbol: CCR2
CCR2
0.050 AlteredExpression phenotype BEFREE Inhibition of PI3K/Akt pathway may partly reduce MCP-1/CCR2-induced expression of P2X4R and mechanical allodynia in CIBP rats. 30776493 2019
Entrez Id: 729230
Gene Symbol: CCR2
CCR2
0.050 Biomarker phenotype BEFREE However, microglial cells activation/proliferation in the spinal cord and mechanical allodynia after SNI were reduced in Ccr2-deficient mice. 31150565 2019
Entrez Id: 729230
Gene Symbol: CCR2
CCR2
0.050 AlteredExpression phenotype BEFREE Therefore, the upregulation of spinal MCP-1 and CCR2 expression levels may contribute to the development of mechanical allodynia in MTBP rats. 28352316 2017
Entrez Id: 729230
Gene Symbol: CCR2
CCR2
0.050 Biomarker phenotype BEFREE Moreover, adoptive transfer of wild-type mouse neutrophils to CCR2-deficient mice restored neutrophil infiltration and the articular mechanical hyperalgesia associated with joint inflammation. 25779331 2015
Entrez Id: 729230
Gene Symbol: CCR2
CCR2
0.050 Biomarker phenotype BEFREE Mice that lack Ccr2 also developed mechanical allodynia, but this started to resolve from 8 wk onwards. 23185004 2012