Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 836
Gene Symbol: CASP3
CASP3 		0.500 Therapeutic phenotype RGD The role of heme oxygenase-1 (HO-1) in the regulation of inflammatory reaction, neuronal cell proliferation and apoptosis in rats after intracerebral hemorrhage (ICH). 28096675 2017
Entrez Id: 841
Gene Symbol: CASP8
CASP8 		0.500 Therapeutic phenotype RGD The role of heme oxygenase-1 (HO-1) in the regulation of inflammatory reaction, neuronal cell proliferation and apoptosis in rats after intracerebral hemorrhage (ICH). 28096675 2017
Entrez Id: 5327
Gene Symbol: PLAT
PLAT 		0.500 Biomarker phenotype CTD_human Reduced estimated glomerular filtration rate is associated with stroke outcome after intravenous rt-PA: the Stroke Acute Management with Urgent Risk-Factor Assessment and Improvement (SAMURAI) rt-PA registry. 21088392 2011
Entrez Id: 5327
Gene Symbol: PLAT
PLAT 		0.500 Biomarker phenotype CTD_human Symptomatic intracerebral hemorrhage among eligible warfarin-treated patients receiving intravenous tissue plasminogen activator for acute ischemic stroke. 20212195 2010
Entrez Id: 5327
Gene Symbol: PLAT
PLAT 		0.500 Biomarker phenotype CTD_human Edaravone, a free radical scavenger, inhibits MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator. 19095969 2009
Entrez Id: 5327
Gene Symbol: PLAT
PLAT 		0.500 Biomarker phenotype CTD_human Symptomatic intracerebral hemorrhage and recanalization after IV rt-PA: a multicenter study. 18753474 2008
Entrez Id: 5327
Gene Symbol: PLAT
PLAT 		0.500 Biomarker phenotype CTD_human NXY-059 for the treatment of acute stroke: pooled analysis of the SAINT I and II Trials. 18369171 2008
Entrez Id: 841
Gene Symbol: CASP8
CASP8 		0.500 Biomarker phenotype CTD_human Matrix metalloproteinase inhibition facilitates cell death in intracerebral hemorrhage in mouse. 17971790 2008
Entrez Id: 5327
Gene Symbol: PLAT
PLAT 		0.500 Biomarker phenotype CTD_human Intravenous recombinant tissue plasminogen activator improves arterial recanalization rates and reduces infarct volumes in patients with hyperdense artery sign on baseline computed tomography. 18346647 2008
Entrez Id: 836
Gene Symbol: CASP3
CASP3 		0.500 Biomarker phenotype CTD_human Matrix metalloproteinase inhibition facilitates cell death in intracerebral hemorrhage in mouse. 17971790 2008
Entrez Id: 5327
Gene Symbol: PLAT
PLAT 		0.500 Biomarker phenotype CTD_human Assessment of suitability of thrombolysis in middle cerebral artery infarction: a proof of concept study of a stereologically-based technique. 17690543 2007
Entrez Id: 2321
Gene Symbol: FLT1
FLT1 		0.500 Biomarker phenotype CTD_human Cerebral angiogenesis after collagenase-induced intracerebral hemorrhage in rats. 17888890 2007
Entrez Id: 2321
Gene Symbol: FLT1
FLT1 		0.500 Biomarker phenotype RGD Cerebral angiogenesis after collagenase-induced intracerebral hemorrhage in rats. 17888890 2007
Entrez Id: 5327
Gene Symbol: PLAT
PLAT 		0.500 Biomarker phenotype CTD_human Argatroban tPA stroke study: study design and results in the first treated cohort. 16908730 2006
Entrez Id: 5327
Gene Symbol: PLAT
PLAT 		0.500 Biomarker phenotype CTD_human Recombinant tissue plasminogen activator for minor strokes: the National Institute of Neurological Disorders and Stroke rt-PA Stroke Study experience. 16126134 2005
Entrez Id: 5327
Gene Symbol: PLAT
PLAT 		0.500 Biomarker phenotype CTD_human Our findings suggest that endogenous tPA plays an important role in heparin-produced cerebral hemorrhage via MMP9 induction and activation. 16190367 2005
Entrez Id: 5327
Gene Symbol: PLAT
PLAT 		0.500 Biomarker phenotype CTD_human Essential role of endogenous tissue plasminogen activator through matrix metalloproteinase 9 induction and expression on heparin-produced cerebral hemorrhage after cerebral ischemia in mice. 14630814 2004
Entrez Id: 5327
Gene Symbol: PLAT
PLAT 		0.500 Therapeutic phenotype RGD Tissue plasminogen activator for the treatment of intraventricular hematoma: the dose-effect relationship. 12220690 2002
Entrez Id: 5327
Gene Symbol: PLAT
PLAT 		0.500 Biomarker phenotype CTD_human Markers of increased risk of intracerebral hemorrhage after intravenous recombinant tissue plasminogen activator therapy for acute ischemic stroke in clinical practice: the Multicenter rt-PA Stroke Survey. 11940547 2002
Entrez Id: 5327
Gene Symbol: PLAT
PLAT 		0.500 Biomarker phenotype CTD_human Early stroke treatment associated with better outcome: the NINDS rt-PA stroke study. 11113218 2000
Entrez Id: 5327
Gene Symbol: PLAT
PLAT 		0.500 Biomarker phenotype CTD_human Brain hemorrhages after rt-PA treatment of embolic stroke in spontaneously hypertensive rats. 10501537 1999
Entrez Id: 5327
Gene Symbol: PLAT
PLAT 		0.500 Biomarker phenotype CTD_human Thrombolysis with intravenous rtPA in a series of 100 cases of acute carotid territory stroke: determination of etiological, topographic, and radiological outcome factors. 9836764 1998
Entrez Id: 5327
Gene Symbol: PLAT
PLAT 		0.500 Biomarker phenotype CTD_human Complications from the use of thrombolytic agents in patients with cocaine associated chest pain. 8969996 1997
Entrez Id: 5327
Gene Symbol: PLAT
PLAT 		0.500 Biomarker phenotype CTD_human Tissue plasminogen activator for acute ischemic stroke. 7477192 1995
Entrez Id: 5327
Gene Symbol: PLAT
PLAT 		0.500 Biomarker phenotype CTD_human Safety and efficacy of intravenous tissue plasminogen activator and heparin in acute middle cerebral artery stroke. 1579960 1992