Gene: H3C1 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 8350
Gene Symbol: H3C1
H3C1 		0.050 GeneticVariation disease BEFREE Recent analyses on the genomic landscape of DIPG revealed recurrent mutations in the H3F3A and HIST1H3B histone genes. 31848724 2020
Entrez Id: 8350
Gene Symbol: H3C1
H3C1 		0.050 GeneticVariation disease BEFREE Genomic studies show that DIPG is driven by somatic mutations to histone H3, either H3.1 or H3.3 variants (HIST1H3B/C and H3F3A), altering the epigenetic landscape of primitive oligodendrocyte or astrocyte precursor cells of the pontine region of the brainstem. 31328874 2019
Entrez Id: 8350
Gene Symbol: H3C1
H3C1 		0.050 GeneticVariation disease BEFREE Nearly 80% of DIPGs harbor a mutation in the H3F3A or the related HIST1H3B gene. 28339768 2017
Entrez Id: 8350
Gene Symbol: H3C1
H3C1 		0.050 GeneticVariation disease BEFREE We found conservation of heterozygous K27M mutations in H3F3A (n = 4) or HIST1H3B (n = 3) across all primary, contiguous, and metastatic tumor sites in all DIPGs. 26727948 2016
Entrez Id: 8350
Gene Symbol: H3C1
H3C1 		0.050 GeneticVariation disease BEFREE Sequencing analysis showed c.83A>T mutations in the H3F3A or HIST1H3B gene in 77 % of our DIPG cohort. 24297113 2014