Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3315
Gene Symbol: HSPB1
HSPB1
0.010 Biomarker disease BEFREE The overexpression of heat shock protein 27 (hsp-27) in early-stage breast cancer is associated with histopathologic features of poor prognosis and clinically with an increased probability of disease recurrence. 7530588 1995
Entrez Id: 3316
Gene Symbol: HSPB2
HSPB2
0.010 Biomarker disease BEFREE The overexpression of heat shock protein 27 (hsp-27) in early-stage breast cancer is associated with histopathologic features of poor prognosis and clinically with an increased probability of disease recurrence. 7530588 1995
Entrez Id: 8988
Gene Symbol: HSPB3
HSPB3
0.010 Biomarker disease BEFREE The overexpression of heat shock protein 27 (hsp-27) in early-stage breast cancer is associated with histopathologic features of poor prognosis and clinically with an increased probability of disease recurrence. 7530588 1995
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.100 Biomarker disease BEFREE Overexpression of p53 and HER-2/neu proteins as prognostic markers in early stage breast cancer. 7909221 1994
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.020 AlteredExpression disease BEFREE Overexpression of p53 and HER-2/neu proteins as prognostic markers in early stage breast cancer. 7909221 1994
Entrez Id: 3875
Gene Symbol: KRT18
KRT18
0.010 AlteredExpression disease BEFREE The PB samples of 31 patients and the BM samples of 34 patients with predominantly early-stage breast cancer were tested for PTHrP expression along with immunocytology against cytokeratin 18 (CK18) as a standard immunological detection technique. 9341902 1997
Entrez Id: 5744
Gene Symbol: PTHLH
PTHLH
0.010 AlteredExpression disease BEFREE The PB samples of 31 patients and the BM samples of 34 patients with predominantly early-stage breast cancer were tested for PTHrP expression along with immunocytology against cytokeratin 18 (CK18) as a standard immunological detection technique. 9341902 1997
Entrez Id: 993
Gene Symbol: CDC25A
CDC25A
0.010 Biomarker disease BEFREE These data suggest that overexpression of Cdc25A contributes to the biological behavior of primary breast tumors and that both Cdc25A and Cdk2 are suitable therapeutic targets in early-stage breast cancer. 10995786 2000
Entrez Id: 1017
Gene Symbol: CDK2
CDK2
0.010 Biomarker disease BEFREE These data suggest that overexpression of Cdc25A contributes to the biological behavior of primary breast tumors and that both Cdc25A and Cdk2 are suitable therapeutic targets in early-stage breast cancer. 10995786 2000
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.100 Biomarker disease BEFREE ErbB2 status and the benefit from two or five years of adjuvant tamoxifen in postmenopausal early stage breast cancer. 11205461 2000
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
0.050 GeneticVariation disease BEFREE Management of early-stage breast cancer in young women with mutations in BRCA1 or BRCA2 remains controversial. 11988246 2002
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
0.020 GeneticVariation disease BEFREE Management of early-stage breast cancer in young women with mutations in BRCA1 or BRCA2 remains controversial. 11988246 2002
Entrez Id: 1027
Gene Symbol: CDKN1B
CDKN1B
0.010 AlteredExpression disease BEFREE High p27Kip1 expression predicts superior relapse-free and overall survival for premenopausal women with early-stage breast cancer receiving adjuvant treatment with tamoxifen plus goserelin. 14512390 2003
Entrez Id: 573
Gene Symbol: BAG1
BAG1
0.010 AlteredExpression disease BEFREE BAG-1 protein species are localized differentially; nuclear expression may be associated with a shorter disease-free and overall survival in early stage breast cancer, while cytoplasmic expression has been associated with longer survival in non-small cell lung cancer. 15026618 2004
Entrez Id: 55540
Gene Symbol: IL17RB
IL17RB
0.030 AlteredExpression disease BEFREE The HOXB13:IL17BR expression ratio may be useful for identifying patients appropriate for alternative therapeutic regimens in early-stage breast cancer. 15193263 2004
Entrez Id: 10481
Gene Symbol: HOXB13
HOXB13
0.030 AlteredExpression disease BEFREE The HOXB13:IL17BR expression ratio may be useful for identifying patients appropriate for alternative therapeutic regimens in early-stage breast cancer. 15193263 2004
Entrez Id: 6422
Gene Symbol: SFRP1
SFRP1
0.020 AlteredExpression disease BEFREE SFRP1 expression might be useful as a novel prognostic marker in early stage breast cancer. 15289865 2004
Entrez Id: 8795
Gene Symbol: TNFRSF10B
TNFRSF10B
0.010 Biomarker disease BEFREE We sought to determine the expression and prognostic value of TRAIL-R1 and TRAIL-R2 in early-stage breast cancer. 16033835 2005
Entrez Id: 8797
Gene Symbol: TNFRSF10A
TNFRSF10A
0.010 AlteredExpression disease BEFREE We sought to determine the expression and prognostic value of TRAIL-R1 and TRAIL-R2 in early-stage breast cancer. 16033835 2005
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.100 AlteredExpression disease BEFREE Impact of Her-2 Neu overexpression on outcome of elderly women treated with wide local excision and breast irradiation for early stage breast cancer: an exploratory analysis. 16462507 2006
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
0.050 GeneticVariation disease BEFREE The results suggest that mutation of PIK3CA might contribute to development of early stage breast cancer and could provide a potent target for early diagnosis and therapy. 16582596 2006
Entrez Id: 3880
Gene Symbol: KRT19
KRT19
0.060 AlteredExpression disease BEFREE The aim of the present study was to decrease the incidence of false positives and to better characterize marginally cytokeratin-19 (CK-19) mRNA positive peripheral blood samples from patients with early stage breast cancer. 16708381 2006
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.100 Biomarker disease BEFREE Thus, trastuzumab is also rapidly becoming a standard component of adjuvant therapy for patients with HER2-positive early-stage breast cancer. 16831025 2006
Entrez Id: 10481
Gene Symbol: HOXB13
HOXB13
0.030 AlteredExpression disease BEFREE The HOXB13:IL17BR expression index is a prognostic factor in early-stage breast cancer. 17008703 2006
Entrez Id: 55540
Gene Symbol: IL17RB
IL17RB
0.030 AlteredExpression disease BEFREE The HOXB13:IL17BR expression index is a prognostic factor in early-stage breast cancer. 17008703 2006