Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.660 | Biomarker | disease | GENOMICS_ENGLAND | |||||||
|
0.660 | Biomarker | disease | BEFREE | Tau protein was implicated in AD pathophysiology and the tau gene haplotype is probably connected with sporadic late-onset Parkinson's disease (PD). | 12932819 | 2003 | ||||
|
0.660 | AlteredExpression | disease | BEFREE | We investigated CSF tau-protein and Abeta42 concentrations in 73 patients with advanced idiopathic Parkinson's disease with dementia (PDD) and 23 patients with idiopathic Parkinson's disease without dementia (PD) and in a comparison group of 41 non-demented neurological patients (CG) using commercially available enzyme-linked-immunoabsorbant-assay (ELISA). tau-Protein levels were statistically significantly higher and Abeta42 lower in the PDD patients compared to PD patients and the CG. | 16899997 | 2006 | ||||
|
0.660 | Biomarker | disease | CTD_human | |||||||
|
0.660 | AlteredExpression | disease | BEFREE | We evaluated the influence of MAPT haplotypes on the expression of motor features in PD patients. | 24253235 | 2014 | ||||
|
0.660 | GeneticVariation | disease | BEFREE | Association of single-nucleotide polymorphisms of the tau gene with late-onset Parkinson disease. | 11710889 | 2001 | ||||
|
0.660 | Biomarker | disease | BEFREE | Here, we report that HR23B and HR23A, proteins that are involved in both DNA repair and shuttling proteins to the 26S proteasome for degradation, accumulate in neuronal inclusions in brain from a mouse model for FXTAS, as well as in brain material from HD, SCA3, SCA7, FTDP-17 and PD patients. | 16860562 | 2006 | ||||
|
0.660 | Biomarker | disease | BEFREE | Our results revealed an association between the abnormal aggregation of α-synuclein, Aβ<sub>42</sub> , and tau proteins and structural connectivity disruption in PD patients. | 29436735 | 2018 | ||||
|
0.660 | CausalMutation | disease | CLINVAR | |||||||
|
0.660 | SusceptibilityMutation | disease | CLINVAR |