Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1490
Gene Symbol: CCN2
CCN2
0.130 Biomarker disease BEFREE Pioglitazone inhibited the canonical TGFβ1-CTGF axis in human pulmonary artery SMC and smLRP1<sup>-/-</sup> main pulmonary artery (CTGF and NOX4) and reversed PAH in smLRP1<sup>-/-</sup> mice. 31023188 2019
Entrez Id: 1490
Gene Symbol: CCN2
CCN2
0.130 Biomarker disease BEFREE ES administration relieved the deregulation of miR-133a, MYOSLID, SRF, and CTGF in PAH rats. 31562386 2019
Entrez Id: 1490
Gene Symbol: CCN2
CCN2
0.130 Biomarker disease BEFREE The present study suggests that PCPA protects against the pathogenesis of PAH by suppressing remodeling and inducing apoptosis, which are likely associated with CTGF and downstream ERK signaling pathway in rats. 29340081 2017
Entrez Id: 1490
Gene Symbol: CCN2
CCN2
0.130 Biomarker disease HPO