Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4093
Gene Symbol: SMAD9
SMAD9
0.660 GeneticVariation disease BEFREE PASMCs were obtained from 12 patients with PAH including 9 patients with idiopathic PAH (IPAH) and 3 patients with heritable PAH (HPAH) (2 patients with BMPR2 mutation and one patient with SMAD9 mutation) who underwent lung transplantation. 30180189 2018
Entrez Id: 4093
Gene Symbol: SMAD9
SMAD9
0.660 GeneticVariation disease BEFREE However, current guidelines, clinical practices, and available gene panels focus the diagnosis of PAH on a relatively low number of genes and variants associated with the bone morphogenic proteins and transforming Growth Factor-β pathways, such as the BMPR2, ACVRL1, CAV1, ENG, and SMAD9. 28768485 2017
Entrez Id: 4093
Gene Symbol: SMAD9
SMAD9
0.660 Biomarker disease GENOMICS_ENGLAND Pulmonary Arterial Hypertension: A Current Perspective on Established and Emerging Molecular Genetic Defects. 26387786 2015
Entrez Id: 4093
Gene Symbol: SMAD9
SMAD9
0.660 GeneticVariation disease BEFREE Correction of nonsense BMPR2 and SMAD9 mutations by ataluren in pulmonary arterial hypertension. 23590310 2013
Entrez Id: 4093
Gene Symbol: SMAD9
SMAD9
0.660 GeneticVariation disease BEFREE We studied a family in which multiple members had pulmonary arterial hypertension without identifiable mutations in any of the genes known to be associated with the disease, including BMPR2, ALK1, ENG, SMAD9, and CAV1. 23883380 2013
Entrez Id: 4093
Gene Symbol: SMAD9
SMAD9
0.660 Biomarker disease BEFREE Our findings suggest the involvement of SMAD8 in the pathogenesis of PAH. 19211612 2009
Entrez Id: 4093
Gene Symbol: SMAD9
SMAD9
0.660 Biomarker disease BEFREE These findings implicate Smad8 in both pulmonary hypertension and lung tumorigenesis and support Smad8 as a candidate gene for PAH in humans. 19419974 2009
Entrez Id: 4093
Gene Symbol: SMAD9
SMAD9
0.660 Biomarker disease HPO
Entrez Id: 4093
Gene Symbol: SMAD9
SMAD9
0.660 Biomarker disease CTD_human