This study explored the effect of Cav-1<sup>F92A</sup>-modified rat bone marrow mesenchymal stem cells (rBMSC/Cav-1<sup>F92A</sup>) on oxidative stress regulation through CA1/kininogen and SelW/14-3-3<i>η</i> signal transduction in a rat model of monocrotaline- (MCT-) induced pulmonary arterial hypertension (PAH).