Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.040 Biomarker disease BEFREE Role of smooth muscle cell p53 in pulmonary arterial hypertension. 30807606 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.040 AlteredExpression disease BEFREE Furthermore, p53 is downregulated in PASMCs isolated from patients with idiopathic pulmonary arterial hypertension compared with PASMCs from normal subjects. 30358436 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.040 Biomarker disease BEFREE Due to the growth-suppressive and pro-apoptotic effects of p53 and its inactivation in cancer, we hypothesized that the p53 pathway could be altered in PAH. 26121334 2015
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.040 GeneticVariation disease BEFREE The frequency of p53 mutations in PAH lesions was 5.3%, which was similar to that in HGPIN lesions (4.2%).Benign glands never showed mutations. 12210488 2002