Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.070 | Biomarker | group | BEFREE | Thus, ASXL1-MT–induced MDS-like disease in mice is associated with derepression of Hoxa9 and miR-125a and with Clec5a dysregulation. | 24216483 | 2013 | ||||
|
0.070 | GeneticVariation | group | BEFREE | NUP98-HOXA9 is associated with the t(7;11)(p15;p15) translocation in acute myeloid leukemia (AML), myelodysplastic syndrome, and blastic crisis of chronic myeloid leukemia. | 17442773 | 2007 | ||||
|
0.070 | GeneticVariation | group | LHGDN | The t(7;11)(p15;p15) translocation, observed in acute myelogenous leukemia and myelodysplastic syndrome, generates a chimeric gene where the 5' portion of the sequence encoding the human nucleoporin NUP98 protein is fused to the 3' region of HOXA9. | 17178874 | 2006 | ||||
|
0.070 | GeneticVariation | group | BEFREE | The t(7;11)(p15;p15) translocation, observed in acute myelogenous leukemia and myelodysplastic syndrome, generates a chimeric gene where the 5' portion of the sequence encoding the human nucleoporin NUP98 protein is fused to the 3' region of HOXA9. | 17178874 | 2006 | ||||
|
0.070 | AlteredExpression | group | BEFREE | These results indicate that CD34(+) cell selection is required to accurately assess the expression levels of HOXA9 and related genes in the multipotential malignant progenitor cells of MDS patients. | 15982348 | 2005 | ||||
|
0.070 | Biomarker | group | BEFREE | The fusion points were similar to previously reported NUP98-HOXA9 fusion points from patients with MDS/AML. | 11241795 | 2001 | ||||
|
0.070 | GeneticVariation | group | BEFREE | NUP98-HOXA9 chimera mRNA, which is known to be involved in t(7;11)(p15;p15) translocation in acute myeloid leukemia (AML), was not detected by reverse transcriptase-polymerase chain reaction, and NUP98 rearrangement was not detected by Southern blot analysis of the blasts in the MDS phase. | 10936866 | 2000 | ||||
|
0.070 | GeneticVariation | group | BEFREE | Molecular heterogeneity of the NUP98/HOXA9 fusion transcript in myelodysplastic syndromes associated with t(7;11)(p15;p15). | 10583265 | 1999 |