Gene: H2AX ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3014
Gene Symbol: H2AX
H2AX 		0.040 Biomarker disease BEFREE SMI#9 attenuated cisplatin-induced PCNA monoubiquitination (TLS marker), FANCD2 (Fanconi anemia (FA) activation marker), and TLS polymerase POL η. SMI#9-induced decreases in γH2AX levels were associated with concomitant inhibition of H2AX monoubiquitination, suggesting a key role for RAD6 in modulating cisplatin-induced γH2AX via H2AX monoubiquitination. 31639439 2020
Entrez Id: 3014
Gene Symbol: H2AX
H2AX 		0.040 Biomarker disease BEFREE The accumulation of γ-H2AX foci in irradiated FA fibroblasts was observed. 24512567 2014
Entrez Id: 3014
Gene Symbol: H2AX
H2AX 		0.040 Biomarker disease BEFREE Consequently, histone H2AX is functionally connected to the FA/BRCA pathway to resolve stalled replication forks and prevent chromosome instability. 17304220 2007
Entrez Id: 3014
Gene Symbol: H2AX
H2AX 		0.040 Biomarker disease BEFREE Here, we discuss a model for the FA pathway and how it could partially explain the common phenotypes of H2AX, BRCA2 and FA deficiencies. 17471025 2007