Gene: MTHFR ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		0.030 GeneticVariation disease BEFREE C677T (rs1801133) polymorphism in MTHFR predicts nonresponse and/or adverse effects of MTX treatment in JIA patients. 29589488 2018
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		0.030 Biomarker disease BEFREE MTHFR genotyping may have a predictive value for the risk of MTX-associated toxicity in patients with JIA. 20595278 2010
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		0.030 GeneticVariation disease BEFREE These preliminary data suggest an association of the MTHFR 677C/C polymorphism to a higher tolerability of MTX, and of the 1298A/A to lower clinical efficacy of MTX therapy in JIA. 16142884 2005