Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 23158
Gene Symbol: TBC1D9
TBC1D9 		0.040 GeneticVariation disease BEFREE A PRISMA-compliant meta-analysis of MDR1 polymorphisms and idiopathic nephrotic syndrome: Susceptibility and steroid responsiveness. 28614261 2017
Entrez Id: 2212
Gene Symbol: FCGR2A
FCGR2A 		0.010 GeneticVariation disease BEFREE A significant association was found between idiopathic nephrotic syndrome and FCGR2A rs1801274 SNP (both with the T allele and the TT genotype, p value=0.0009, OR 1.81, 95% CI 1.27-2.59 and p value=0.0007, OR 2.39, 95% CI 1.44-3.99, respectively). 29155175 2018
Entrez Id: 7827
Gene Symbol: NPHS2
NPHS2 		0.680 CausalMutation disease CLINVAR A single-gene cause in 29.5% of cases of steroid-resistant nephrotic syndrome. 25349199 2015
Entrez Id: 7827
Gene Symbol: NPHS2
NPHS2 		0.680 GeneticVariation disease CLINVAR A single-gene cause in 29.5% of cases of steroid-resistant nephrotic syndrome. 25349199 2015
Entrez Id: 126859
Gene Symbol: AXDND1
AXDND1 		0.100 GeneticVariation disease CLINVAR A single-gene cause in 29.5% of cases of steroid-resistant nephrotic syndrome. 25349199 2015
Entrez Id: 126859
Gene Symbol: AXDND1
AXDND1 		0.100 CausalMutation disease CLINVAR A single-gene cause in 29.5% of cases of steroid-resistant nephrotic syndrome. 25349199 2015
Entrez Id: 7827
Gene Symbol: NPHS2
NPHS2 		0.680 GeneticVariation disease UNIPROT A spectrum of novel NPHS1 and NPHS2 gene mutations in pediatric nephrotic syndrome patients from Pakistan. 22565185 2012
Entrez Id: 7827
Gene Symbol: NPHS2
NPHS2 		0.680 CausalMutation disease CLINVAR A spectrum of novel NPHS1 and NPHS2 gene mutations in pediatric nephrotic syndrome patients from Pakistan. 22565185 2012
Entrez Id: 126859
Gene Symbol: AXDND1
AXDND1 		0.100 CausalMutation disease CLINVAR A spectrum of novel NPHS1 and NPHS2 gene mutations in pediatric nephrotic syndrome patients from Pakistan. 22565185 2012
Entrez Id: 83715
Gene Symbol: ESPN
ESPN 		0.010 Biomarker disease BEFREE A survey was sent to all members of the ESPN on behalf of the "Renal Transplantation" and "Idiopathic Nephrotic Syndrome" working groups. 30825259 2019
Entrez Id: 54474
Gene Symbol: KRT20
KRT20 		0.020 Biomarker disease BEFREE Adverse events linked with the use of chimeric and humanized anti-CD20 antibodies in children with idiopathic nephrotic syndrome. 29436729 2018
Entrez Id: 931
Gene Symbol: MS4A1
MS4A1 		0.020 Biomarker disease BEFREE Adverse events linked with the use of chimeric and humanized anti-CD20 antibodies in children with idiopathic nephrotic syndrome. 29436729 2018
Entrez Id: 1636
Gene Symbol: ACE
ACE 		0.080 GeneticVariation disease BEFREE An assessment of the association between ACE I/D gene polymorphism and idiopathic nephrotic syndrome (INS) susceptibility in children is still controversial. 21946394 2011
Entrez Id: 7827
Gene Symbol: NPHS2
NPHS2 		0.680 GeneticVariation disease CLINVAR Analysis of NPHS1, NPHS2, ACTN4, and WT1 in Japanese patients with congenital nephrotic syndrome. 15780077 2005
Entrez Id: 7827
Gene Symbol: NPHS2
NPHS2 		0.680 GeneticVariation disease CLINVAR Analysis of NPHS2 mutations in Turkish steroid-resistant nephrotic syndrome patients. 16810518 2006
Entrez Id: 7827
Gene Symbol: NPHS2
NPHS2 		0.680 GeneticVariation disease CLINVAR Anemia in congenital nephrotic syndrome: role of urinary copper and ceruloplasmin loss. 21636722 2011
Entrez Id: 50964
Gene Symbol: SOST
SOST 		0.010 Biomarker disease BEFREE Assessment of the Concentration of Bone Metabolism Markers: Sclerostin and FGF-23 in Children with Idiopathic Nephrotic Syndrome Treated with Glucocorticosteroids. 31354894 2019
Entrez Id: 8074
Gene Symbol: FGF23
FGF23 		0.010 Biomarker disease BEFREE Assessment of the Concentration of Bone Metabolism Markers: Sclerostin and FGF-23 in Children with Idiopathic Nephrotic Syndrome Treated with Glucocorticosteroids. 31354894 2019
Entrez Id: 7827
Gene Symbol: NPHS2
NPHS2 		0.680 GeneticVariation disease CLINVAR Association between NPHS1 and NPHS2 gene variants and nephrotic syndrome in children. 25599733 2015
Entrez Id: 1636
Gene Symbol: ACE
ACE 		0.080 Biomarker disease BEFREE Association of ACE and MDR1 Gene Polymorphisms with Steroid Resistance in Children with Idiopathic Nephrotic Syndrome. 26154535 2015
Entrez Id: 1909
Gene Symbol: EDNRA
EDNRA 		0.010 GeneticVariation disease BEFREE Association of endothelin receptor type A rs5333 gene polymorphism with steroid response in Egyptian children with idiopathic nephrotic syndrome. 30672385 2019
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1 		0.050 GeneticVariation disease BEFREE Association of ACE and MDR1 Gene Polymorphisms with Steroid Resistance in Children with Idiopathic Nephrotic Syndrome. 26154535 2015
Entrez Id: 23158
Gene Symbol: TBC1D9
TBC1D9 		0.040 GeneticVariation disease BEFREE Association of ACE and MDR1 Gene Polymorphisms with Steroid Resistance in Children with Idiopathic Nephrotic Syndrome. 26154535 2015
Entrez Id: 7345
Gene Symbol: UCHL1
UCHL1 		0.010 Biomarker disease BEFREE Autoantibodies against podocytic UCHL1 are associated with idiopathic nephrotic syndrome relapses and induce proteinuria in mice. 29307588 2018
Entrez Id: 1906
Gene Symbol: EDN1
EDN1 		0.010 Biomarker disease BEFREE BackgroundThe pathogenesis of idiopathic nephrotic syndrome (INS) remains unclear, although recent studies suggest endothelin 1 (ET-1) and CD80 of podocytes are involved. 29360807 2018