Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6289
Gene Symbol: SAA2
SAA2
0.090 AlteredExpression disease BEFREE Monitoring SAA level in attack-free FMF patients is recommended in order to adjust colchicine dose, and minimize the risk of AA amyloidosis. 27838405 2017
Entrez Id: 6289
Gene Symbol: SAA2
SAA2
0.090 Biomarker disease BEFREE This significant result indicates that a normal f-SAA will indicate a minimal or even absent risk of succumbing to AA amyloidosis. 19657764 2009
Entrez Id: 6289
Gene Symbol: SAA2
SAA2
0.090 Biomarker disease BEFREE AA amyloidosis invariably has been associated with fibrillar deposits of the acute phase high-density lipoprotein serum amyloid A isotypes SAA1 and SAA2. 20536400 2009
Entrez Id: 6289
Gene Symbol: SAA2
SAA2
0.090 GeneticVariation disease BEFREE To investigate the precise modality of association between SAA1 gene polymorphisms and the development of AA amyloidosis in patients with rheumatoid arthritis (RA), Japanese patients with RA (n=153), among whom 29 were histologically diagnosed as having amyloidosis, were genotyped for three single nucleotide polymorphisms (SNPs), C-13T, C2995T, and C3010T, in the SAA gene. 17039310 2006
Entrez Id: 6289
Gene Symbol: SAA2
SAA2
0.090 Biomarker disease BEFREE Prolonged hyperexpression of SAA protein accompanying chronic inflammation is critical to, but seems not to be sufficient for, the development of AA amyloidosis. 12762135 2003
Entrez Id: 6289
Gene Symbol: SAA2
SAA2
0.090 GeneticVariation disease BEFREE To examine whether polymorphism at the SAA loci is associated with the development of amyloid protein A (AA)-amyloidosis, we determined the genotypes at the SAA1 and SAA2 loci in 43 AA-amyloidosis patients (amyloidosis population) and 77 patients with rheumatoid arthritis (RA) who had been ill for less than 5 years (early RA population). 10543406 1999
Entrez Id: 6289
Gene Symbol: SAA2
SAA2
0.090 Biomarker disease BEFREE Chronically elevated A-SAA concentrations are a prerequisite for the pathogenesis of secondary amyloidosis, a progressive and fatal disease characterized by the deposition in major organs of insoluble plaques composed principally of proteolytically cleaved A-SAA, and may also contribute to physiological processes that lead to atherosclerosis. 9729453 1998
Entrez Id: 6289
Gene Symbol: SAA2
SAA2
0.090 Biomarker disease BEFREE SAA1 is the predominant isoform of acute phase human SAA deposited as AA amyloid fibrils in reactive systemic amyloidosis. 10036584 1998
Entrez Id: 6289
Gene Symbol: SAA2
SAA2
0.090 Biomarker disease BEFREE AA-amyloidosis. Tissue component-specific association of various protein AA subspecies and evidence of a fourth SAA gene product. 2386201 1990