Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 952
Gene Symbol: CD38
CD38
0.070 AlteredExpression disease BEFREE A high expression of CD49d (>30%) was found in 142/415 (34%) patients and was associated with progressive disease (advanced clinical stage, high serum lactate dehydrogenase or β2 -microglobulin levels; all p < 0·05) and aggressive disease biology (increased ZAP70 or CD38, unmutated IGHV, trisomy 12, mutations of NOTCH1 and SF3B1; all P < 0·05). 26559905 2016
Entrez Id: 952
Gene Symbol: CD38
CD38
0.070 Biomarker disease BEFREE We undertook a longitudinal study close to diagnosis, pre-treatment and post relapse in 13 patients presenting with cMBL or Stage A disease and good-risk biomarkers (IGHV-M genes, no del(17p) or del(11q) and low CD38 expression) who nevertheless developed progressive disease, of whom 10 have required therapy. 26847028 2016
Entrez Id: 952
Gene Symbol: CD38
CD38
0.070 AlteredExpression disease BEFREE In addition, mutated IgHV1-69 gene status was associated with lower cell surface CD38 expression and less progressive disease as monitored by Binet staging, lymphocyte doubling time and requirement of chemotherapeutic intervention. 18398745 2008
Entrez Id: 952
Gene Symbol: CD38
CD38
0.070 AlteredExpression disease BEFREE CD38 expression level and pattern of expression remains a reliable and robust marker of progressive disease in chronic lymphocytic leukemia. 17107912 2006
Entrez Id: 952
Gene Symbol: CD38
CD38
0.070 AlteredExpression disease BEFREE Cell-surface expression of CD38 in CLL has been recognised recently as a marker of progressive disease and poor outcome. 16019444 2005
Entrez Id: 952
Gene Symbol: CD38
CD38
0.070 AlteredExpression disease BEFREE All expressed CD38 and had a progressive disease. 15466924 2005
Entrez Id: 952
Gene Symbol: CD38
CD38
0.070 GeneticVariation disease BEFREE The presence of a distinct CD38(+) population within the leukemic clone, rather than a numerical cutoff definition, correlates with IgV(H) gene mutational status and, irrespective of its size, identifies CLL patients who will have progressive disease. 12406914 2003